[{"additionalPlain":"Melody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.\n","additional":"Melody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"Melody","location":"Pasadena, CA","team":"Melody","allLocations":["Pasadena, CA"]},"createdAt":1779780849186,"descriptionPlain":"Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications. \nWe are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.\nAbout the role: we are hiring a bioelectronics engineer to build and run our foundry approach which integrates protein biosensor and device engineering. This role is for those who are systems-minded experimentalists and engineers and care about constraints early on that will help make a product work in real world settings. You own the wet side of the interface and, in the early days, you will do whatever the foundry needs most. As the team grows, this role becomes the technical owner of biosensor integration, directing development towards performance in real world settings.\nYou may excel in this role if you enjoy owning science and engineering projects “soup to nuts” (in our case, from protein to in vivo experiments), mapping R&D systems to lab workflows that our team can execute, integrating molecular biology, materials chemistry, and electronics, and working closely with a team spanning those fields. Specifically, you will:\nLead Melody’s wetware integration strategy across biosensor proteins, surface chemistry, hydrogels, membranes, and readout hardware.\nDesign diagnostic experiments that distinguish biosensor failure from immobilization failure, hydrogel diffusion limits, biofluid matrix effects, optical artifacts, electrochemical artifacts, fouling, drift, or hardware noise.\nExecute directed evolution workflows and guide protein design based on these results.\nSynthesize or adapt materials for bioelectronics interfaces.\nMerge novel device hardware with these proteins and materials in close collaboration with the hardware team.\nHelp automate fabrication and assay workflows using our robotics.\nWhat success looks like:\nIn 3 months - set up foundry experimentation end-to-end with a focus on ensuring a tight feedback loop for protein engineering.\nIn 6 months - design a novel biosensing scheme (e.g., highly multiplexed readout) and test on the benchtop.\nIn 15 months - refine wet-facing parts for initial in vivo studies and prepare to iterate based on those results.\nRequired Qualifications:\nPhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).\nDeep expertise in two or more of these areas with working competence across them: protein engineering, protein expression/purification, bioconjugation, surface chemistry, hydrogels or biomaterials, optical biosensing, electrochemical biosensing, microfluidics, assay automation, biofluid assay development, and biofouling characterization and mitigation.\nAbility to build or customize instrumentation for protein biophysics, optics, and electrochemistry.\nQuantitative judgment for designing experiments under real-world constraints, matching roadmap goals to instrument capabilities and lab throughput.\nDemonstrated precision in experimental work and scientific project management.\nStrong technical communication skills across the relevant scientific fields and teams.\nPreferred Qualifications:\n3+ years industry experience in device engineering, particularly molecular sensing and medical device design.\n2+ years industry experience in medical device manufacturing.\nAbility to write custom scripts for data analysis and interfacing with lab instruments.\nConceptual command of the electronic nose field.\n2+ years of team management and mentoring experience. We are especially interested in those with a track record of coordinating across chemists, materials scientists, hardware engineers, software/data scientists, vendors, and academic collaborators.\n","description":"\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
About the role: we are hiring a bioelectronics engineer to build and run our foundry approach which integrates protein biosensor and device engineering. This role is for those who are systems-minded experimentalists and engineers and care about constraints early on that will help make a product work in real world settings. You own the wet side of the interface and, in the early days, you will do whatever the foundry needs most. As the team grows, this role becomes the technical owner of biosensor integration, directing development towards performance in real world settings.
\n
You may excel in this role if you enjoy owning science and engineering projects “soup to nuts” (in our case, from protein to in vivo experiments), mapping R&D systems to lab workflows that our team can execute, integrating molecular biology, materials chemistry, and electronics, and working closely with a team spanning those fields. Specifically, you will:
\n
\n- \n
Lead Melody’s wetware integration strategy across biosensor proteins, surface chemistry, hydrogels, membranes, and readout hardware.
\n \n- \n
Design diagnostic experiments that distinguish biosensor failure from immobilization failure, hydrogel diffusion limits, biofluid matrix effects, optical artifacts, electrochemical artifacts, fouling, drift, or hardware noise.
\n \n- \n
Execute directed evolution workflows and guide protein design based on these results.
\n \n- \n
Synthesize or adapt materials for bioelectronics interfaces.
\n \n- \n
Merge novel device hardware with these proteins and materials in close collaboration with the hardware team.
\n \n- \n
Help automate fabrication and assay workflows using our robotics.
\n \n
\n
What success looks like:
\n
In 3 months - set up foundry experimentation end-to-end with a focus on ensuring a tight feedback loop for protein engineering.
\n
In 6 months - design a novel biosensing scheme (e.g., highly multiplexed readout) and test on the benchtop.
\n
In 15 months - refine wet-facing parts for initial in vivo studies and prepare to iterate based on those results.
\n
Required Qualifications:
\n
\n- \n
PhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).
\n \n- \n
Deep expertise in two or more of these areas with working competence across them: protein engineering, protein expression/purification, bioconjugation, surface chemistry, hydrogels or biomaterials, optical biosensing, electrochemical biosensing, microfluidics, assay automation, biofluid assay development, and biofouling characterization and mitigation.
\n \n- \n
Ability to build or customize instrumentation for protein biophysics, optics, and electrochemistry.
\n \n- \n
Quantitative judgment for designing experiments under real-world constraints, matching roadmap goals to instrument capabilities and lab throughput.
\n \n- \n
Demonstrated precision in experimental work and scientific project management.
\n \n- \n
Strong technical communication skills across the relevant scientific fields and teams.
\n \n
\n
Preferred Qualifications:
\n
\n- \n
3+ years industry experience in device engineering, particularly molecular sensing and medical device design.
\n \n- 2+ years industry experience in medical device manufacturing.
\n- \n
Ability to write custom scripts for data analysis and interfacing with lab instruments.
\n \n- \n
Conceptual command of the electronic nose field.
\n \n- \n
2+ years of team management and mentoring experience. We are especially interested in those with a track record of coordinating across chemists, materials scientists, hardware engineers, software/data scientists, vendors, and academic collaborators.
\n \n
\n
\n
Salary leveled based on experience and fit.
\n
\n
We offer:
\n
\n- 401k match up to 6% of base salary.
\n- Excellent health, vision, and dental benefits.
\n- Paid time off and company holidays.
\n
\n
\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
About the role: we are hiring a bioelectronics engineer to build and run our foundry approach which integrates protein biosensor and device engineering. This role is for those who are systems-minded experimentalists and engineers and care about constraints early on that will help make a product work in real world settings. You own the wet side of the interface and, in the early days, you will do whatever the foundry needs most. As the team grows, this role becomes the technical owner of biosensor integration, directing development towards performance in real world settings.
\n
You may excel in this role if you enjoy owning science and engineering projects “soup to nuts” (in our case, from protein to in vivo experiments), mapping R&D systems to lab workflows that our team can execute, integrating molecular biology, materials chemistry, and electronics, and working closely with a team spanning those fields. Specifically, you will:
\n
\n- \n
Lead Melody’s wetware integration strategy across biosensor proteins, surface chemistry, hydrogels, membranes, and readout hardware.
\n \n- \n
Design diagnostic experiments that distinguish biosensor failure from immobilization failure, hydrogel diffusion limits, biofluid matrix effects, optical artifacts, electrochemical artifacts, fouling, drift, or hardware noise.
\n \n- \n
Execute directed evolution workflows and guide protein design based on these results.
\n \n- \n
Synthesize or adapt materials for bioelectronics interfaces.
\n \n- \n
Merge novel device hardware with these proteins and materials in close collaboration with the hardware team.
\n \n- \n
Help automate fabrication and assay workflows using our robotics.
\n \n
\n
What success looks like:
\n
In 3 months - set up foundry experimentation end-to-end with a focus on ensuring a tight feedback loop for protein engineering.
\n
In 6 months - design a novel biosensing scheme (e.g., highly multiplexed readout) and test on the benchtop.
\n
In 15 months - refine wet-facing parts for initial in vivo studies and prepare to iterate based on those results.
\n
Required Qualifications:
\n
\n- \n
PhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).
\n \n- \n
Deep expertise in two or more of these areas with working competence across them: protein engineering, protein expression/purification, bioconjugation, surface chemistry, hydrogels or biomaterials, optical biosensing, electrochemical biosensing, microfluidics, assay automation, biofluid assay development, and biofouling characterization and mitigation.
\n \n- \n
Ability to build or customize instrumentation for protein biophysics, optics, and electrochemistry.
\n \n- \n
Quantitative judgment for designing experiments under real-world constraints, matching roadmap goals to instrument capabilities and lab throughput.
\n \n- \n
Demonstrated precision in experimental work and scientific project management.
\n \n- \n
Strong technical communication skills across the relevant scientific fields and teams.
\n \n
\n
Preferred Qualifications:
\n
\n- \n
3+ years industry experience in device engineering, particularly molecular sensing and medical device design.
\n \n- 2+ years industry experience in medical device manufacturing.
\n- \n
Ability to write custom scripts for data analysis and interfacing with lab instruments.
\n \n- \n
Conceptual command of the electronic nose field.
\n \n- \n
2+ years of team management and mentoring experience. We are especially interested in those with a track record of coordinating across chemists, materials scientists, hardware engineers, software/data scientists, vendors, and academic collaborators.
\n \n
\n
E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"E11 Bio","location":"Alameda, California","team":"E11 Bio","allLocations":["Alameda, California"]},"createdAt":1772670536959,"descriptionPlain":"E11 Bio is a nonprofit organization tackling a neuroscience moonshot: developing a radical technology platform for scalable mammalian brain mapping. E11 is a Focused Research Organization supported by Convergent Research. Our work will have an impact for neuroscience, the next generation of AI, but most importantly for the millions of people who suffer from neurological disorders. We are a collaborative, interdisciplinary team of scientists and engineers working at the frontier of connectomics. Read our technology roadmap.\n \nE11 Bio is seeking an experienced Operations Lead to manage and mentor a small ops team and provide operational leadership across the organization’s systems.\n \nThis is a full-time, exempt leadership role responsible for ensuring scientific activities are supported by operational execution, managing the operations team, and building scalable systems that support E11’s continued growth. You will partner closely with scientific leadership to guide planning, manage risk, and ensure that ambitious technical goals are matched by operational rigor.\nThis is an onsite role based in Alameda, CA.\n","description":"E11 Bio is a nonprofit organization tackling a neuroscience moonshot: developing a radical technology platform for scalable mammalian brain mapping. E11 is a
Focused Research Organization supported by Convergent Research. Our work will have an impact for neuroscience, the next generation of AI, but most importantly for the millions of people who suffer from neurological disorders. We are a collaborative, interdisciplinary team of scientists and engineers working at the frontier of connectomics. Read our
technology roadmap.
\n
\nE11 Bio is seeking an experienced Operations Lead to manage and mentor a small ops team and provide operational leadership across the organization’s systems.
\n
\nThis is a full-time, exempt leadership role responsible for ensuring scientific activities are supported by operational execution, managing the operations team, and building scalable systems that support E11’s continued growth. You will partner closely with scientific leadership to guide planning, manage risk, and ensure that ambitious technical goals are matched by operational rigor.
\nThis is an onsite role based in Alameda, CA.
","id":"c20fa761-1eae-4b8b-995d-93745896382e","lists":[{"text":"Responsibilities","content":"\nProject Management\nGuide project planning processes across programs to ensure clarity of priorities, timelines, and interdependencies.\nTrack project status across initiatives, proactively flagging risk and improving cross-project communication.\nReduce organizational risk by daylighting project blockers, coordinating managerial response, and ensuring disciplined follow-through.\n\n
\n\nOperational & Process Leadership\nDirectly manage the operations team, including the Scientific Operations Manager, Lab Manager, and Office Coordinator.\nIntroduce and institutionalize best practices in operational management.\nEvolve internal processes to be scalable, robust, and resilient as the organization grows.\nForecast resource needs 1–2 quarters in advance, including capital purchases and operational capacity.\nStrengthen planning cadence and execution discipline across teams.\n\n
\n\nFinancial Oversight & Contracts\nSupport financial forecasting and expenditure discipline across programs.\nOversee contracts related to partnerships, facilities, vendors, and contractors in coordination with legal and accounting partners.\n\n
\n\nPeople Leadership & Mentorship\nProvide direct supervision, coaching, and development to members of the operations team.\nOffer developmentally relevant feedback and mentorship to managers and senior contributors across the organization.\nIntroduce best practices in personnel management, performance feedback, and accountability.\nStrengthen a culture of professionalism, mutual respect, and operational excellence.\n"},{"text":"Qualifications","content":"\nRequired:\n8+ years of experience in operational roles within technical or scientific organizations + a track record of successful operational leadership.\nExperience directly mentoring and managing individual contributors.\nStrong financial literacy, including budget review, forecasting, and vendor contract oversight.\nExperience building or scaling operational systems in a growing organization.\nProven ability to execute strategy through operational excellence.\nDemonstrated project management experience.\nExperience advising leadership on personnel management.\nStrong judgment, risk assessment, and organizational design skills.\nExcellent communication skills and ability to build alignment across senior stakeholders.\nAbility to work onsite in a highly collaborative, mission-driven environment.\nStrong references from managers, peers, and direct reports.\n\n
\n\nNice to have (not required):\nExperienced with meeting management and group dynamics: Driving the agenda, keeping the meeting on track, surfacing action items and tracking them to completion.\nSpecific experience related to Neurotechnology, biotechnology, or a related scientific field.\nExperience in a research-focused nonprofit or startup environment.\nFamiliarity with capital equipment planning and laboratory infrastructure scaling.\n"},{"text":"What success looks like","content":"\nBy three months, you will have:\nBuilt trust with scientific and operational leadership.\nDeveloped fluency in E11’s project roadmap, financial structure, and project portfolio.\nClarified project tracking and reporting expectations across programs.\nIdentified areas of operational risk and begun implementing improvements.\n\n
\n\nBy one year, you will have:\nSignificantly strengthened cross-program alignment and reduced ambiguity in planning and execution.\nImplemented scalable operational and financial systems that support organizational growth.\nBuilt a cohesive, high-functioning operations team with clear roles and strong accountability.\nPositioned E11 for continued expansion through disciplined forecasting and process maturity.\n"},{"text":"Who will love this job","content":"\nYou enjoy building structure around ambitious science.\nYou are energized by aligning technical vision with operational execution.\nYou like mentoring others and elevating organizational standards.\nYou are comfortable navigating financial and logistical detail.\nYou are motivated by high-impact, mission-driven neuroscience.\n"},{"text":"We offer","content":"\nA senior leadership opportunity at the forefront of scalable connectomics.\nFull-time, exempt role based onsite in Alameda, CA.\nExcellent medical, dental, and vision insurance; parental leave.\n6% 401K match\nGenerous time off + paid holidays.\nAmple healthy food including daily lunches.\nWellness allowance for fitness and wellness activities.\nWork with impact. Your leadership will shape the operational foundation of a field-defining scientific effort.\n"}],"salaryRange":{"min":180000,"max":200000,"currency":"USD","interval":"per-year-salary"},"salaryDescription":"Base salary range: 180k - 200k
\nBonus: Performance-based, up to 20% of base salary
\n401k match: up to 6% of base salary
\nTotal potential compensation range: 227k - 252k
","salaryDescriptionPlain":"Base salary range: 180k - 200k\nBonus: Performance-based, up to 20% of base salary\n401k match: up to 6% of base salary\nTotal potential compensation range: 227k - 252k\n","text":"E11 Bio - Operations Lead","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"E11 Bio is a nonprofit organization tackling a neuroscience moonshot: developing a radical technology platform for scalable mammalian brain mapping. E11 is a
Focused Research Organization supported by Convergent Research. Our work will have an impact for neuroscience, the next generation of AI, but most importantly for the millions of people who suffer from neurological disorders. We are a collaborative, interdisciplinary team of scientists and engineers working at the frontier of connectomics. Read our
technology roadmap.
\n
\nE11 Bio is seeking an experienced Operations Lead to manage and mentor a small ops team and provide operational leadership across the organization’s systems.
\n
\nThis is a full-time, exempt leadership role responsible for ensuring scientific activities are supported by operational execution, managing the operations team, and building scalable systems that support E11’s continued growth. You will partner closely with scientific leadership to guide planning, manage risk, and ensure that ambitious technical goals are matched by operational rigor.
\nThis is an onsite role based in Alameda, CA.
","descriptionBodyPlain":"E11 Bio is a nonprofit organization tackling a neuroscience moonshot: developing a radical technology platform for scalable mammalian brain mapping. E11 is a Focused Research Organization supported by Convergent Research. Our work will have an impact for neuroscience, the next generation of AI, but most importantly for the millions of people who suffer from neurological disorders. We are a collaborative, interdisciplinary team of scientists and engineers working at the frontier of connectomics. Read our technology roadmap.\n \nE11 Bio is seeking an experienced Operations Lead to manage and mentor a small ops team and provide operational leadership across the organization’s systems.\n \nThis is a full-time, exempt leadership role responsible for ensuring scientific activities are supported by operational execution, managing the operations team, and building scalable systems that support E11’s continued growth. You will partner closely with scientific leadership to guide planning, manage risk, and ensure that ambitious technical goals are matched by operational rigor.\nThis is an onsite role based in Alameda, CA.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/c20fa761-1eae-4b8b-995d-93745896382e","applyUrl":"https://jobs.lever.co/convergentresearch/c20fa761-1eae-4b8b-995d-93745896382e/apply"},{"additionalPlain":"E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.\n","additional":"E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"E11 Bio","location":"Alameda, California","team":"E11 Bio","allLocations":["Alameda, California"]},"createdAt":1770836852178,"descriptionPlain":"E11 Bio is a Focused Research Organization (FRO) with a long-term mission to make connectomics scalable and cost-effective for mammalian brains – first for mice and eventually for humans. \n\nWe have recently developed PRISM, a platform technology for low cost optical connectomics. PRISM integrates advances in genetic cell barcoding, multiplexed expansion microscopy, and machine-learning based -based spatial reconstruction to solve key bottlenecks in data acquisition and analysis. PRISM will reduce the cost of connectomics 100-fold and thereby transform neuroscience, treatments for brain disorders, and neuro-inspired computing. \n\n\nE11 Bio is seeking a mission-aligned experimental scientist who is equally comfortable at the bench, the microscope, and with quantitative data analysis. This role is responsible for sample preparation end-to-end for high-quality connectomics, combining hands-on experimental work with quantitative image-based QC to diagnose failure modes and iteratively improve protocols. You will collaborate closely with molecular biology, imaging, and computational teams to ensure we consistently prepare high quality specimens and brain tissue to support our ambitious scaling goals towards whole-brain connectomics.\n","description":"E11 Bio is a Focused Research Organization (FRO) with a long-term mission to make connectomics scalable and cost-effective for mammalian brains – first for mice and eventually for humans.
We have recently developed PRISM, a platform technology for low cost optical connectomics. PRISM integrates advances in genetic cell barcoding, multiplexed expansion microscopy, and machine-learning based -based spatial reconstruction to solve key bottlenecks in data acquisition and analysis. PRISM will reduce the cost of connectomics 100-fold and thereby transform neuroscience, treatments for brain disorders, and neuro-inspired computing.
E11 Bio is seeking a mission-aligned experimental scientist who is equally comfortable at the bench, the microscope, and with quantitative data analysis. This role is responsible for sample preparation end-to-end for high-quality connectomics, combining hands-on experimental work with quantitative image-based QC to diagnose failure modes and iteratively improve protocols. You will collaborate closely with molecular biology, imaging, and computational teams to ensure we consistently prepare high quality specimens and brain tissue to support our ambitious scaling goals towards whole-brain connectomics.
","id":"0ffc5537-3eb4-43b1-aa7e-c32da0db35de","lists":[{"text":"Core Responsibilities","content":"Ensure consistent end-to-end quality across our in vivo sample preparation pipeline. Collaborate with technicians, including viral delivery and animal perfusion, tissue processing, and overall readiness for imaging and molecular readoutsPerform and troubleshoot stereotaxic injections and perfusions as needed to optimize our in vivo sample preparation pipeline and guide protocol improvementsRoutinely evaluate injection and perfusion outcomes (viral labeling, tissue quality, use for downstream work) through microscopy and image analysisDefine, implement, and maintain sample quality rubrics (e.g. labeling density, barcode density) and ensure samples are scored consistently over timeDevelop and maintain image-based workflows to generate quantitative QC metrics based on partnership and feedback with wet lab and computational staffDesign and perform experiments to improve sample quality when it is limiting for downstream applicationsExtend quality assessment to RNA integrity and molecular preservation"},{"text":"Required Qualifications","content":"Ph.D. in neuroscience, biology, bioengineering, or a related life-science or engineering field, or Ph.D.-equivalent working record3–5 years of relevant research experience with a strong track record of end-to-end experimental ownershipDemonstrated hands-on experience with in vivo sample preparation, including stereotaxic injections, perfusions, and tissue handlingExperience acquiring and working with confocal and widefield microscopy dataExperience developing or maintaining fit-for-purpose image-analysis workflows (e.g. Python scripts, Fiji macros, or equivalent) to support experimental iterationStrong organizational, documentation, and record-keeping practices and strong attention to reproducibilityExcellent communication and collaboration skills, particularly across wet-lab, imaging, and computational teams"},{"text":"Preferred Qualifications","content":"Experience designing or applying quality control rubrics or scoring systems for biological samples or imaging dataFamiliarity with image-analysis pipelines for cell counting, morphology, spatial distributions, or intensity-based metricsExperience working in highly iterative or startup-like research environments and in work where roles span multiple technical domains"},{"text":"We offer","content":"An opportunity to help change the world and work with a world-class interdisciplinary team of scientists and engineers on a field-defining moonshotExcellent medical, dental, and vision insurance through a PPO plan; parental leave.Generous time off + paid holidays.401K matching up to 6% of base salaryAmple healthy and energizing food including daily lunches.Stipend for fitness and wellness activities."}],"salaryRange":{"min":96000,"max":144000,"currency":"USD","interval":"per-year-salary"},"salaryDescription":"Base salary range: 96k - 144k
Bonus: Performance-based, up to 20% of base salary
401k match: up to 6% of base salary
Total potential compensation range: 121k - 181k
","salaryDescriptionPlain":"Base salary range: 96k - 144k\nBonus: Performance-based, up to 20% of base salary\n401k match: up to 6% of base salary\nTotal potential compensation range: 121k - 181k\n","text":"E11 Bio - Scientist, Tissue & Imaging Quality","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"E11 Bio is a Focused Research Organization (FRO) with a long-term mission to make connectomics scalable and cost-effective for mammalian brains – first for mice and eventually for humans.
We have recently developed PRISM, a platform technology for low cost optical connectomics. PRISM integrates advances in genetic cell barcoding, multiplexed expansion microscopy, and machine-learning based -based spatial reconstruction to solve key bottlenecks in data acquisition and analysis. PRISM will reduce the cost of connectomics 100-fold and thereby transform neuroscience, treatments for brain disorders, and neuro-inspired computing.
E11 Bio is seeking a mission-aligned experimental scientist who is equally comfortable at the bench, the microscope, and with quantitative data analysis. This role is responsible for sample preparation end-to-end for high-quality connectomics, combining hands-on experimental work with quantitative image-based QC to diagnose failure modes and iteratively improve protocols. You will collaborate closely with molecular biology, imaging, and computational teams to ensure we consistently prepare high quality specimens and brain tissue to support our ambitious scaling goals towards whole-brain connectomics.
","descriptionBodyPlain":"E11 Bio is a Focused Research Organization (FRO) with a long-term mission to make connectomics scalable and cost-effective for mammalian brains – first for mice and eventually for humans. \n\nWe have recently developed PRISM, a platform technology for low cost optical connectomics. PRISM integrates advances in genetic cell barcoding, multiplexed expansion microscopy, and machine-learning based -based spatial reconstruction to solve key bottlenecks in data acquisition and analysis. PRISM will reduce the cost of connectomics 100-fold and thereby transform neuroscience, treatments for brain disorders, and neuro-inspired computing. \n\n\nE11 Bio is seeking a mission-aligned experimental scientist who is equally comfortable at the bench, the microscope, and with quantitative data analysis. This role is responsible for sample preparation end-to-end for high-quality connectomics, combining hands-on experimental work with quantitative image-based QC to diagnose failure modes and iteratively improve protocols. You will collaborate closely with molecular biology, imaging, and computational teams to ensure we consistently prepare high quality specimens and brain tissue to support our ambitious scaling goals towards whole-brain connectomics.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/0ffc5537-3eb4-43b1-aa7e-c32da0db35de","applyUrl":"https://jobs.lever.co/convergentresearch/0ffc5537-3eb4-43b1-aa7e-c32da0db35de/apply"},{"additionalPlain":"E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.\n","additional":"E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"E11 Bio","location":"Alameda, California","team":"E11 Bio","allLocations":["Alameda, California"]},"createdAt":1769195405487,"descriptionPlain":"E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our technology roadmap.\n \nHigh quality tissue samples are the foundation of our science. We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.\n","description":"E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our
technology roadmap.
\n
\nHigh quality tissue samples are the foundation of our science. We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.
","id":"cc0978b1-4003-44b7-8fa7-045312807a7a","lists":[{"text":"Responsibilities","content":"\nTake ownership of all animal perfusions, including preparation of perfusates, execution of procedures, troubleshooting tissue-quality issues, and continuous improvement of fixation protocols.\nExecute and support in vivo surgical workflows, including stereotaxic and retro-orbital viral injections, post-operative monitoring, and animal welfare documentation.\nApply scientific training to monitor, control, and systematically optimize key in vivo and perfusion parameters for tissue labeling + preservation.\nCollaborate closely with experimental scientists to design, execute, and troubleshoot in vivo labeling experiments, contributing technical judgment and experimental insight.\nPerform routine animal health checks and husbandry tasks as needed, with attention to health or behavioral changes that may impact experimental outcomes.\nMaintain accurate experimental records, reproducible protocols, and operational readiness of perfusion and surgical equipment.\nContribute to a positive, collaborative lab culture and run small, focused experimental projects.\n"},{"text":"Required Qualifications","content":"\nHands-on experience performing animal perfusions using PFA or related fixatives for neuroscience or brain tissue applications, with the ability to produce consistent, high-quality tissue.\nDemonstrated ability to quickly learn, independently own, and optimize complex biological workflows, including diagnosing and resolving tissue-quality or protocol failures.\nExperience with rodent handling, restraint, and basic health assessment in a research setting.\nStrong record of reliability, precision, and careful experimental documentation.\nClear communication skills and a proven ability to collaborate effectively within interdisciplinary research teams.\n"},{"text":"Preferred Qualifications","content":"\nMechanical or technical aptitude for maintaining, adjusting, or troubleshooting perfusion rigs, surgical setups, and related laboratory hardware.\nExperience with in vivo surgical techniques such as stereotaxic or retro-orbital viral injections (or strong interest and aptitude to train into these methods).\nFamiliarity with downstream histology, imaging, or molecular tissue workflows.\nInterest in neuroscience and connectomics, with motivation to contribute to technically demanding, high-impact research.\n"},{"text":"In the first 3 months…","content":"\nBy 1 month: You will have taken on core colony management at E11 (breeding, weaning, genotyping workflows, health checks, record keeping), completed training in stereotaxic and retro-orbital injections, and be learning and performing perfusions at our baseline quality level under supervision.\nAfter 2 months: You will be independently performing perfusions and generating consistent, high-quality tissue. You will be running routine surgeries with good survival and recovery, and managing the colony reliably end-to-end.\nAfter 3 months: You will be piloting controlled perturbations to the perfusion workflow—adjusting pressure, flow, temperature, perfusate composition, cannula/needle configurations—and documenting QC outcomes to improve ultrastructure, RNA retention, and protein preservation.\nAfter 1 year: You will own and direct execution and scheduling of perfusions at E11. You will be routinely producing well QCed tissue .\n"},{"text":"We offer:","content":"\nAn opportunity to help change the world and work with some of the most talented and collaborative experts across scientific fields.\nAn opportunity to gain experience on a field-defining moonshot effort.\nExcellent medical, dental, and vision insurance through a PPO plan; parental leave.\nGenerous time off + paid holidays.\n401K matching up to 6% of base salary\nAmple healthy and energizing food including daily lunches.\nStipend for fitness and wellness activities.\n"}],"salaryRange":{"min":90000,"max":144000,"currency":"USD","interval":"per-year-salary"},"salaryDescription":"Base salary range: $90,000 to $144,000 annually
\nBonus: Performance-based, up to 20% of base salary
\n401K match: 6%
\nTotal potential compensation: $113,400 - 181,440 annually
","salaryDescriptionPlain":"Base salary range: $90,000 to $144,000 annually\nBonus: Performance-based, up to 20% of base salary\n401K match: 6%\nTotal potential compensation: $113,400 - 181,440 annually\n","text":"E11 Bio - Senior Research Associate - in vivo","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our
technology roadmap.
\n
\nHigh quality tissue samples are the foundation of our science. We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.
","descriptionBodyPlain":"E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our technology roadmap.\n \nHigh quality tissue samples are the foundation of our science. We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/cc0978b1-4003-44b7-8fa7-045312807a7a","applyUrl":"https://jobs.lever.co/convergentresearch/cc0978b1-4003-44b7-8fa7-045312807a7a/apply"},{"additionalPlain":"Convergent Research aims to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D.\nWe are committed to creating an inclusive and diverse workplace where everyone has the opportunity to thrive. We believe in hiring individuals based on their unique talents—not on race, color, religion, ethnicity, gender, gender identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by law or our company policies. We are more than a proud Equal Employment Opportunity employer. Our goal is to foster a healthy, safe, and respectful environment where all employees are valued and treated with dignity. Harassment of any kind is not tolerated here. #LI-remote #LI-KP1\n","additional":"\n
Convergent Research aims to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D.
\n
We are committed to creating an inclusive and diverse workplace where everyone has the opportunity to thrive. We believe in hiring individuals based on their unique talents—not on race, color, religion, ethnicity, gender, gender identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by law or our company policies. We are more than a proud Equal Employment Opportunity employer. Our goal is to foster a healthy, safe, and respectful environment where all employees are valued and treated with dignity. Harassment of any kind is not tolerated here. #LI-remote #LI-KP1
\n
\n
Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We’re launching moonshot science projects which may change the trajectory of scientific progress. Large scale brain mapping, climate measurement, and software for math all have something in common - they each need a nonprofit legal entity, payroll providers, health benefits, boards, contracts, office space, press releases, websites… For each of the FROs that Convergent Research supports, we provide the backend infrastructure to help them move fast.
\n
\n
About the Role
\n
As the Finance and Accounting Manager, you will play a key role in managing financial operations across Convergent and its FROs. Reporting to the Head of Finance, you will collaborate with internal teams and external partners to ensure financial scalability, compliance, and alignment with our mission.
\n
This is a fully remote position with domestic travel required quarterly for team and organizational onsites, and as needed.
\n
\n\n
\nA nonprofit accounting pro. You understand nonprofit accounting principles, including fund accounting, restricted vs. unrestricted donations, and government grants. You enjoy solving complex reconciliation challenges and exercise a passion for ensuring financial accuracy.
\n\n
\nAudit-seasoned. You have participated in quite a few audits (and single audits) and are comfortable with 990s.
\n\n
\nFederal grants fluent. You understand federal grant compliance. You have managed a few federal grants in your time and speak of federal agencies by their acronyms.
\n\n
\nPleasantly detail-obsessed. You sweat the details, but don’t get hung up on immaterial ones. You know when it’s appropriate to push back for compliance or GAAP sake.
\n\n
\nSystems-savvy. You enjoy working with multiple systems and have a firm grasp of accounting systems. You know when to ask for systems help too!
\n\n
\nA natural collaborator. You can translate a complex journal entry into plain English for a non-finance colleague without breaking a sweat.
\n\n\n
\n\n
\nOwn the close. You oversee monthly reconciliation and close across your FROs — and at the consolidated level, covering treasury, PR/AR/AP, payroll, and other liabilities.
\n\n
\nKeep grant reporting on track. You provide financial oversight for grants and maintain detailed financial reports for FROs and government entities.
\n\n
\nTurn numbers into insight. As first line reviewer of monthly financial reports, you review monthly financials for relevancy, consistency, and completeness — and advocate for changes that make reports actually useful for decision-making.
\n\n
\nGet audit ready. You assist with audit processes– including preparing schedules and supporting 990 filings.
\n\n
\nBring the whole team along. You make financial insights accessible and actionable — whether you're talking to a scientist, an engineer, or a program lead.
\n\n
\nStrengthen systems and processes. You help improve workflows, maintain SOPs, and keep internal controls tight.
\n\n\n
\n\n
\nLearned a lot about who Convergent is, what we have to say about ourselves, and who our various audiences are.
\n\n
\nBuilt strong relationships with internal teams, external accounting partners, and FRO leaders.
\n\n
\nLearn the business of your FROs and understand their finance and accounting needs.
\n\n\n
\n\n
\nA rare chance to build institutional architecture for frontier science and work with some of the smartest and most talented experts from different fields
\n\n
\nCompetitive Salary: The salary range for this role is $111,000 - 159,000 Convergent uses a consistent compensation philosophy across all roles. We benchmark salaries to San Francisco market data and aim for the grade midpoint, which for this role is approximately $159,000. We then apply a geographic adjustment if an employee is located outside of SF, NYC, or Boston, For example, in Denver, CO the midpoint for this role would be around $135k, and in Eugene, OR it would be $119k. We also maintain a minimum of 70% of the SF midpoint, which is reflected in the range floor. This structure helps us keep pay transparent, consistent, and equitable across locations while reflecting local market conditions.
\n\n
\nUp to a 6% 401k match because future-you deserves comfort
\n\n
\nTop-tier medical, dental, and vision insurance—majority of options are fully covered for you and your dependents. Stay healthy, my friend
\n\n
\nCompany-paid life insurance, AD&D, long- and short-term disability insurance, as well as voluntary supplemental insurance options
\n\n
\n19 holidays (including a full week off at the end of the year—yes, we enforce it)
\n\n
\n3 weeks PTO with tenure increases, with separate allotments for sick and parental leave
\n\n
\nGenerous fertility benefits and childcare reimbursement—because tiny humans are a big deal
\n\n
\nEducation and professional development benefits
\n\n
\nWellness allowance for fitness and wellness activities (treat yourself to climbing shoes or Calm.com—no judgment)
\n\n
\n3x/year offsite team retreats and additional opportunities to meet your teammates in person
\n\n\n
\n
Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We’re launching moonshot science projects which may change the trajectory of scientific progress. Large scale brain mapping, climate measurement, and software for math all have something in common - they each need a nonprofit legal entity, payroll providers, health benefits, boards, contracts, office space, press releases, websites… For each of the FROs that Convergent Research supports, we provide the backend infrastructure to help them move fast.
\n
\n
About the Role
\n
As the Finance and Accounting Manager, you will play a key role in managing financial operations across Convergent and its FROs. Reporting to the Head of Finance, you will collaborate with internal teams and external partners to ensure financial scalability, compliance, and alignment with our mission.
\n
This is a fully remote position with domestic travel required quarterly for team and organizational onsites, and as needed.
\n
Convergent Research is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind. #LI-remote #LI-KP1
","categories":{"commitment":"Full Time","department":"Convergent Research","location":"Remote US","team":"Convergent Research","allLocations":["Remote US"]},"createdAt":1780510883660,"descriptionPlain":"Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We architect pivotal infrastructure that removes bottlenecks to breakthrough scientific research.\nFROs are a new operating model for science that ensures rapid iteration cycles and high-throughput learning. Convergent secures funding and provides an operational backbone for counterfactual R&D, creating space for scientists to do what they do best. FRO teams are agile, creative, and risk-tolerant as a result. They make fast progress because they start and stay focused.\nAbout the Role\nConvergent Research now supports 13 active FROs — independent research organizations spanning neuroscience, climate, biology, and beyond — and growing. Our communications function has matured significantly: our narrative is strong, our brand is established, and our external presence has taken shape. What we need now is a communications expert who can own the function, scale it intelligently, and help the scientists building some of the world's most ambitious research organizations learn to tell their stories.\nThe Head of Communications & FRO Engagement leads Convergent's communications function across two interconnected responsibilities: building the communications capabilities of our FRO portfolio and running Convergent's own internal and digital communications. The primary focus of this role is building and scaling communications capabilities across our FRO portfolio. You will teach FRO teams how to develop a media strategy. You'll help scientific founders understand their audiences, build their public voice, and prepare for press. You'll run workshops, coach CEOs, and connect FROs to the right resources to execute\nOn the Convergent side, you'll manage the internal and owned channels and coordinate with external agencies and consultants for brand storytelling and media. You’ll ensure that things are getting shipped and keep the machine running.\nWe anticipate the split to be approximately 85% FRO portfolio communications; 15% Convergent communications. \nWe know this is a wide role. We'd rather find someone who can genuinely do both the coaching and the execution. If the balance isn't perfect, we want someone with the self-awareness to know which leg they stand on — and the resourcefulness to fill the other through consultants, vendors, or AI tools.\nThis role reports to the General Manager and works closely with Convergent's executive team, FRO CEOs, and a curated network of external communications vendors and consultants.\n \n","description":"Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We architect pivotal infrastructure that removes bottlenecks to breakthrough scientific research.
\nFROs are a new operating model for science that ensures rapid iteration cycles and high-throughput learning. Convergent secures funding and provides an operational backbone for counterfactual R&D, creating space for scientists to do what they do best. FRO teams are agile, creative, and risk-tolerant as a result. They make fast progress because they start and stay focused.
\nAbout the Role
\nConvergent Research now supports 13 active FROs — independent research organizations spanning neuroscience, climate, biology, and beyond — and growing. Our communications function has matured significantly: our narrative is strong, our brand is established, and our external presence has taken shape. What we need now is a communications expert who can own the function, scale it intelligently, and help the scientists building some of the world's most ambitious research organizations learn to tell their stories.
\nThe Head of Communications & FRO Engagement leads Convergent's communications function across two interconnected responsibilities: building the communications capabilities of our FRO portfolio and running Convergent's own internal and digital communications. The primary focus of this role is building and scaling communications capabilities across our FRO portfolio. You will teach FRO teams how to develop a media strategy. You'll help scientific founders understand their audiences, build their public voice, and prepare for press. You'll run workshops, coach CEOs, and connect FROs to the right resources to execute
\nOn the Convergent side, you'll manage the internal and owned channels and coordinate with external agencies and consultants for brand storytelling and media. You’ll ensure that things are getting shipped and keep the machine running.
\nWe anticipate the split to be approximately 85% FRO portfolio communications; 15% Convergent communications.
\nWe know this is a wide role. We'd rather find someone who can genuinely do both the coaching and the execution. If the balance isn't perfect, we want someone with the self-awareness to know which leg they stand on — and the resourcefulness to fill the other through consultants, vendors, or AI tools.
\nThis role reports to the General Manager and works closely with Convergent's executive team, FRO CEOs, and a curated network of external communications vendors and consultants.
\n
","id":"bce09cd3-da5d-4c82-b72a-8499f8a4da10","lists":[{"text":"You Are","content":"\nA senior communications generalist with functional ownership instincts – You've led or owned a communications function before — not just contributed to one. You understand the full picture: narrative, media relations, digital channels, brand, internal comms, and the operational infrastructure that holds it together. You know what good looks like and you hold yourself and your work to that standard.\nA communications teacher and coach – You can walk into a room with a scientific founder who has never thought about audiences or media strategy, earn their trust, and shift how they think — not by lecturing, but by asking the right questions. You know how to move someone from \"what pictures and words should I make?\" to a real strategy: who do I need to reach, what do I need them to do, and what's in it for them? You come away from those conversations with a deliverable the FRO actually owns. You are comfortable doing this across wildly different scientific and technological domains\nPR-savvy and media-strategic – You know how to turn complex scientific and technical work into stories that earn attention from the right audiences. You can identify what is genuinely newsworthy, build targeted media strategies, consult on developing strong pitches and briefing materials, prepare founders for press, and manage reporter relationships with judgment and credibility. You help FROs move from “we should get press” to a clear PR strategy: who needs to hear this, why now, what do we want them to understand or do, and which media channels are actually worth pursuing.\nOperationally disciplined– You run a tight ship. Editorial calendars, FRO comms pipelines, vendor timelines, Notion documentation — you own these things without being asked and you keep them current. You also know how to teach others to do the same, and develop templates and systems to make execution easy. \nComfortable with complexity and multiplicity – You are supporting 13 independent organizations, each with their own stage, leadership style, and communications posture. Some want a lot of help; some think they don't need any. You navigate those dynamics with good judgment and without taking it personally.\n\nA resourceful self-starter – You're past the stage of needing hand-holding. You figure things out, build workflows, and know when to escalate versus when to just handle it. You've used AI tools enough to know they change what one person can accomplish — and you're genuinely excited about that, not threatened by it.
\n\nResilient and adaptable – You can push back on a founder who wants to go a different direction, absorb feedback from three different FRO CEOs with conflicting opinions, and still produce something coherent and on time. You don't need everyone to agree to move forward.\n"},{"text":"You Will","content":"\n\n
\nTeach FRO teams how to develop a media and communications strategy –Help FRO teams build a real communications strategy — audience mapping, outcome prioritization, content and channel planning. You facilitate; they build. They leave with something they own and can act on.
\n\n
\nCoach FRO CEOs and scientific leaders on media readiness – Prepare FRO leaders to talk to journalists, find their public voice, and think through their Q&A before they're in the room. Some will ask for this; some will need a nudge. You make the coaching genuinely useful, you know when to push, and you know when to stand down.
\n\n
\nServe as the primary communications resource for FRO teams – Be the first call when an FRO has a communications question, need, or problem. Help them think clearly about what they're trying to accomplish. Connect them to curated vendor and consultant resources. Review anything that carries Convergent's or a funder's name before it goes out.
\n\n
\nCurate and manage the external vendor and consultant network – Build and maintain Convergent's roster of vetted communications vendors — PR firms, video producers, designers, science writers — and help FRO and Convergent leadership navigate it when they need execution support. This isn't about agencies on retainer; it's about a lean, responsive network that can be accessed on demand.
\n\n
\nOwn Convergent's internal and FRO-facing communications – Run the newsletter, the FRO update digest, and the internal knowledge base. Keep these consistent, current, and increasingly automated — and build the systems that make them sustainable as the portfolio grows.
\n\n
\nManage Convergent's owned digital channels – Keep the website current, coordinate social media, and manage the editorial calendar for the Convergent blog and announcements. Serve as the day-to-day internal contact for external web development and multimedia vendors.
\n\n
\nCoordinate press and media for FRO and Convergent announcements – Manage the logistics of press releases, media briefings, and launch announcements. Support executive and FRO CEO media preparation. Maintain relationships with external PR vendors for outbound media work, with clear judgment about where agency value is real and where it isn't.
\n\n
\nProtect the Convergent brand across the portfolio – Ensure external communications carrying Convergent's name or a funder's name meet quality and messaging standards. Part quality control, part relationship-building — you're the person who knows what's going out and flags what needs a second look.
\n\n
\nLeverage AI to scale your reach – Use AI tools for newsletter generation, content summarization, and workflow automation. Help build systems that let Convergent's communications function scale with the portfolio without scaling headcount proportionally.
\n\n\n
\n\n
\nAudited Convergent's current communications workflows, Notion documentation, and editorial calendar — and rebuilt or improved what isn't working.
\n\n
\nGotten to know each active FRO team's communications context, posture, and immediate needs, and established yourself as a trusted and responsive resource.
\n\n
\nTaken full ownership of the internal newsletter, FRO update digest, website maintenance, and social media calendar.
\n\n
\nFacilitated at least one FRO communications workshop and developed a repeatable format and materials for future use.
\n\n
\nCoached at least two FRO leaders through media preparation for a press interaction, publication announcement, or public launch.
\n\n
\nReviewed and rationalized Convergent's external vendor and consultant relationships, and begun building a curated, accessible vendor directory for FROs.
\n\n
\nEstablished clear quality and brand standards for FRO-external communications that carry Convergent's name.
\n\n\n
\n\n
\nA rare chance to work at the frontier of science and help shape how some of the most ambitious research organizations in the world communicate their work
\n\n
\nCompetitive salary with up to a 6% 401k match (base salary range: $165,000-170,000, based on location) While we believe this range reflects the right level for this role, we are open to adjusting the salary level and grade upward for an exceptionally strong candidate.
\n\n
\nExcellent medical insurance options: 10–20 plans to choose from across major national and local carriers. Employee and family premiums for most plans are fully covered by the Company contribution.
\n\n
\nExcellent dental and vision insurance. Employee and family premiums for most plans are fully covered by the Company contribution.
\n\n
\nCompany-paid life insurance, AD&D, long- and short-term disability insurance, as well as voluntary supplemental insurance options
\n\n
\n19 holidays (including a full week off at the end of the year—yes, we enforce it)
\n\n
\n3 weeks PTO with tenure increases, with separate allotments for sick and parental leave
\n\n
\nGenerous fertility benefits and childcare reimbursement
\n\n
\nEducation and professional development benefits
\n\n
\nWellness allowance for fitness and wellness activities
\n\n
\n3x/year offsite team retreats and additional opportunities to meet your teammates in person
\n\n
\nSupport for fully remote work
\n\n\n
Convergent uses a consistent compensation philosophy across all roles. We benchmark salaries to San Francisco market data and aim for the grade midpoint, which for this role is approximately $165,000-170,000. We then apply a geographic adjustment if an employee is located outside of SF, NYC, or Boston, For example, in Denver, CO the midpoint for this role would be around $135k, and in Eugene, OR it would be $119k. We also maintain a minimum of 70% of the SF midpoint. This structure helps us keep pay transparent, consistent, and equitable across locations while reflecting local market conditions and alignment with nonprofit tax requirements. While we believe this range reflects the right level for this role, we are open to adjusting the salary level and grade upward for an exceptionally strong candidate.
","salaryDescriptionPlain":"Convergent uses a consistent compensation philosophy across all roles. We benchmark salaries to San Francisco market data and aim for the grade midpoint, which for this role is approximately $165,000-170,000. We then apply a geographic adjustment if an employee is located outside of SF, NYC, or Boston, For example, in Denver, CO the midpoint for this role would be around $135k, and in Eugene, OR it would be $119k. We also maintain a minimum of 70% of the SF midpoint. This structure helps us keep pay transparent, consistent, and equitable across locations while reflecting local market conditions and alignment with nonprofit tax requirements. While we believe this range reflects the right level for this role, we are open to adjusting the salary level and grade upward for an exceptionally strong candidate.\n","text":"Head of Communications & Engagement","country":"US","workplaceType":"remote","opening":"","openingPlain":"","descriptionBody":"Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We architect pivotal infrastructure that removes bottlenecks to breakthrough scientific research.
\nFROs are a new operating model for science that ensures rapid iteration cycles and high-throughput learning. Convergent secures funding and provides an operational backbone for counterfactual R&D, creating space for scientists to do what they do best. FRO teams are agile, creative, and risk-tolerant as a result. They make fast progress because they start and stay focused.
\nAbout the Role
\nConvergent Research now supports 13 active FROs — independent research organizations spanning neuroscience, climate, biology, and beyond — and growing. Our communications function has matured significantly: our narrative is strong, our brand is established, and our external presence has taken shape. What we need now is a communications expert who can own the function, scale it intelligently, and help the scientists building some of the world's most ambitious research organizations learn to tell their stories.
\nThe Head of Communications & FRO Engagement leads Convergent's communications function across two interconnected responsibilities: building the communications capabilities of our FRO portfolio and running Convergent's own internal and digital communications. The primary focus of this role is building and scaling communications capabilities across our FRO portfolio. You will teach FRO teams how to develop a media strategy. You'll help scientific founders understand their audiences, build their public voice, and prepare for press. You'll run workshops, coach CEOs, and connect FROs to the right resources to execute
\nOn the Convergent side, you'll manage the internal and owned channels and coordinate with external agencies and consultants for brand storytelling and media. You’ll ensure that things are getting shipped and keep the machine running.
\nWe anticipate the split to be approximately 85% FRO portfolio communications; 15% Convergent communications.
\nWe know this is a wide role. We'd rather find someone who can genuinely do both the coaching and the execution. If the balance isn't perfect, we want someone with the self-awareness to know which leg they stand on — and the resourcefulness to fill the other through consultants, vendors, or AI tools.
\nThis role reports to the General Manager and works closely with Convergent's executive team, FRO CEOs, and a curated network of external communications vendors and consultants.
\n
","descriptionBodyPlain":"Convergent Research is a non-profit science studio best known for pioneering the Focused Research Organization (FRO). We architect pivotal infrastructure that removes bottlenecks to breakthrough scientific research.\nFROs are a new operating model for science that ensures rapid iteration cycles and high-throughput learning. Convergent secures funding and provides an operational backbone for counterfactual R&D, creating space for scientists to do what they do best. FRO teams are agile, creative, and risk-tolerant as a result. They make fast progress because they start and stay focused.\nAbout the Role\nConvergent Research now supports 13 active FROs — independent research organizations spanning neuroscience, climate, biology, and beyond — and growing. Our communications function has matured significantly: our narrative is strong, our brand is established, and our external presence has taken shape. What we need now is a communications expert who can own the function, scale it intelligently, and help the scientists building some of the world's most ambitious research organizations learn to tell their stories.\nThe Head of Communications & FRO Engagement leads Convergent's communications function across two interconnected responsibilities: building the communications capabilities of our FRO portfolio and running Convergent's own internal and digital communications. The primary focus of this role is building and scaling communications capabilities across our FRO portfolio. You will teach FRO teams how to develop a media strategy. You'll help scientific founders understand their audiences, build their public voice, and prepare for press. You'll run workshops, coach CEOs, and connect FROs to the right resources to execute\nOn the Convergent side, you'll manage the internal and owned channels and coordinate with external agencies and consultants for brand storytelling and media. You’ll ensure that things are getting shipped and keep the machine running.\nWe anticipate the split to be approximately 85% FRO portfolio communications; 15% Convergent communications. \nWe know this is a wide role. We'd rather find someone who can genuinely do both the coaching and the execution. If the balance isn't perfect, we want someone with the self-awareness to know which leg they stand on — and the resourcefulness to fill the other through consultants, vendors, or AI tools.\nThis role reports to the General Manager and works closely with Convergent's executive team, FRO CEOs, and a curated network of external communications vendors and consultants.\n \n","hostedUrl":"https://jobs.lever.co/convergentresearch/bce09cd3-da5d-4c82-b72a-8499f8a4da10","applyUrl":"https://jobs.lever.co/convergentresearch/bce09cd3-da5d-4c82-b72a-8499f8a4da10/apply"},{"additionalPlain":"We aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.\n \nWe are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.","additional":"We aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"Parallel Squared Technology Institute","location":"Watertown, MA","team":"PTI","allLocations":["Watertown, MA"]},"createdAt":1752254362141,"descriptionPlain":"Parallel Squared Technology Institute (PTI) is a non-profit research institute developing technologies, reagents, and computational tools to increase the sensitivity and throughput of protein analysis, with a specific focus on single-cell proteomics. We are applying these innovations to societally-relevant areas of biomedical research. As part of these efforts, we are developing new approaches to study protein dysfunctions in Alzheimer’s and related neurodegenerative diseases.\n\nSummary of Position\nWe are seeking scientist and senior scientist candidates to help drive our efforts to use single-cell proteomics to understand the causes of Alzheimer’s and related neurodegenerative diseases. Ideal candidates will have expertise in the molecular mechanisms of neurodegeneration and direct, hand-on experience in single-cell analysis, computational biology, and brain tissue handling. \n\nCandidates will have the opportunity to work as part of an interdisciplinary team in multiple areas, including on NIH-funded projects, using proteomic technologies developed at PTI to discover new molecular mechanisms of neurodegeneration in Alzheimer’s and related disorders. Day-to-day responsibilities include designing and carrying out experiments to isolate and profile single cells from brain tissue, computationally analyzing large-scale single-cell proteomics datasets, preparing manuscripts and presentations, mentoring junior scientists, and regular meetings with collaborators in and outside of PTI. Candidates will initially work on ongoing projects but will have the opportunity to design and lead their own projects as well. \n\nCandidates with less than 1 year of postdoctoral experience will be considered for the scientist position and those with more than 1 year of experience will be considered for the senior scientist position. \n\nAbout PTI\nPTI is a nonprofit, focused research organization (FRO) established through Convergent Research. FROs aim to accelerate progress across science and technology by tackling large-scale problems with the potential to unlock existing bottlenecks in specific research areas. PTI aims to achieve a 100-1000x increase in the scale of proteomic analysis. To do so, we are developing new technologies and approaches for mass spectrometric proteomics. This includes molecular barcodes, termed “mass tags” that enable sample multiplexing, as well as computational approaches for increasing the sensitivity of protein analysis. We aim to apply these advances in societally-relevant areas, with a specific focus on neurodegenerative disease. To do so, we are collaborating with leaders in neurodegenerative disease from around the world. To learn more about PTI’s approach for studying neurodegenerative disease, please visit this page. To learn more about our technology for increasing the throughput of protein analysis, please visit here. \n\nResearchers at PTI have the opportunity to work within an interdisciplinary team of mass spectrometrists, chemists, computational analysts, and biologists to push the boundaries of protein analysis. PTI supports professional development through educational opportunities such as travel to conferences workshops. \n\nMembers of PTI receive industry-level resources to lead research projects and have the opportunity to disseminate their discoveries and innovations through high-visibility publications, presentations, and submissions to public data portals. \n","description":"Parallel Squared Technology Institute (PTI) is a non-profit research institute developing technologies, reagents, and computational tools to increase the sensitivity and throughput of protein analysis, with a specific focus on single-cell proteomics. We are applying these innovations to societally-relevant areas of biomedical research. As part of these efforts, we are developing new approaches to study protein dysfunctions in Alzheimer’s and related neurodegenerative diseases.
Summary of Position
We are seeking scientist and senior scientist candidates to help drive our efforts to use single-cell proteomics to understand the causes of Alzheimer’s and related neurodegenerative diseases. Ideal candidates will have expertise in the molecular mechanisms of neurodegeneration and direct, hand-on experience in single-cell analysis, computational biology, and brain tissue handling.
Candidates will have the opportunity to work as part of an interdisciplinary team in multiple areas, including on NIH-funded projects, using proteomic technologies developed at PTI to discover new molecular mechanisms of neurodegeneration in Alzheimer’s and related disorders. Day-to-day responsibilities include designing and carrying out experiments to isolate and profile single cells from brain tissue, computationally analyzing large-scale single-cell proteomics datasets, preparing manuscripts and presentations, mentoring junior scientists, and regular meetings with collaborators in and outside of PTI. Candidates will initially work on ongoing projects but will have the opportunity to design and lead their own projects as well.
Candidates with less than 1 year of postdoctoral experience will be considered for the scientist position and those with more than 1 year of experience will be considered for the senior scientist position.
About PTI
PTI is a nonprofit, focused research organization (FRO) established through Convergent Research. FROs aim to accelerate progress across science and technology by tackling large-scale problems with the potential to unlock existing bottlenecks in specific research areas. PTI aims to achieve a 100-1000x increase in the scale of proteomic analysis. To do so, we are developing new technologies and approaches for mass spectrometric proteomics. This includes molecular barcodes, termed “mass tags” that enable sample multiplexing, as well as computational approaches for increasing the sensitivity of protein analysis. We aim to apply these advances in societally-relevant areas, with a specific focus on neurodegenerative disease. To do so, we are collaborating with leaders in neurodegenerative disease from around the world. To learn more about PTI’s approach for studying neurodegenerative disease, please visit this page. To learn more about our technology for increasing the throughput of protein analysis, please visit here.
Researchers at PTI have the opportunity to work within an interdisciplinary team of mass spectrometrists, chemists, computational analysts, and biologists to push the boundaries of protein analysis. PTI supports professional development through educational opportunities such as travel to conferences workshops.
Members of PTI receive industry-level resources to lead research projects and have the opportunity to disseminate their discoveries and innovations through high-visibility publications, presentations, and submissions to public data portals.
","id":"82540c08-47ab-457a-bc22-f9abf5e0c427","lists":[{"text":"Responsibilities:","content":"Design and execute research projects using single-cell proteomics to understand the molecular mechanisms of neurodegeneration in Alzheimer’s and related disease. Computationally analyze large-scale, single-cell proteomic datasets to identify new molecular mechanisms of disease.Collaborate with external laboratories, brain banks, and tissue repositories on sample procurement.Prepare human brain tissue samples for proteomic analysis using methods and technologies developed at PTI.Help junior scientists gain expertise in experimental techniques used at PTI, analyzing and interpreting experimental results, recording data in laboratory notebooks, and writing up and presenting research results.Make regular presentations within PTI and to collaborators.Prepare manuscripts related to project outcomes and grant applications for external funding.Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.Other duties as assigned."},{"text":"Qualifications: ","content":"PhD Neuroscience or a related field.Direct, hands-on experience in preparing human brain tissue for downstream analyses. Direct, hands-on experience with single cell analysis.Excellent communication and interpersonal skills, record keeping ability, and attention to detail."},{"text":"Preferred Qualifications","content":"Experience in high throughput or automated tissue sample collection, preparation, and analysis, particularly with human brains.Experience with mass spectrometry proteomics.Fluency in R or Python, particularly in the context of single-cell analysis."},{"text":"We offer:","content":"An opportunity to change the world and work with some of the smartest and the most talented experts from different fields.Excellent medical, dental, and vision insurance with many $0 premium options for you and your family with several national and regional providers. Most employees have more than 20 plan options to choose from.Company-paid group life, AD&D, long- and short-term disability insurance15 days PTO + 10 sick days per year18 company holidays + your birthday off$5,000 per year educational reimbursementUp to 16 weeks paid parental leave"}],"salaryRange":{"min":86000,"max":119000,"currency":"USD","interval":"per-year-salary"},"text":"Neurodegenerative Disease Senior Scientist","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"Parallel Squared Technology Institute (PTI) is a non-profit research institute developing technologies, reagents, and computational tools to increase the sensitivity and throughput of protein analysis, with a specific focus on single-cell proteomics. We are applying these innovations to societally-relevant areas of biomedical research. As part of these efforts, we are developing new approaches to study protein dysfunctions in Alzheimer’s and related neurodegenerative diseases.
Summary of Position
We are seeking scientist and senior scientist candidates to help drive our efforts to use single-cell proteomics to understand the causes of Alzheimer’s and related neurodegenerative diseases. Ideal candidates will have expertise in the molecular mechanisms of neurodegeneration and direct, hand-on experience in single-cell analysis, computational biology, and brain tissue handling.
Candidates will have the opportunity to work as part of an interdisciplinary team in multiple areas, including on NIH-funded projects, using proteomic technologies developed at PTI to discover new molecular mechanisms of neurodegeneration in Alzheimer’s and related disorders. Day-to-day responsibilities include designing and carrying out experiments to isolate and profile single cells from brain tissue, computationally analyzing large-scale single-cell proteomics datasets, preparing manuscripts and presentations, mentoring junior scientists, and regular meetings with collaborators in and outside of PTI. Candidates will initially work on ongoing projects but will have the opportunity to design and lead their own projects as well.
Candidates with less than 1 year of postdoctoral experience will be considered for the scientist position and those with more than 1 year of experience will be considered for the senior scientist position.
About PTI
PTI is a nonprofit, focused research organization (FRO) established through Convergent Research. FROs aim to accelerate progress across science and technology by tackling large-scale problems with the potential to unlock existing bottlenecks in specific research areas. PTI aims to achieve a 100-1000x increase in the scale of proteomic analysis. To do so, we are developing new technologies and approaches for mass spectrometric proteomics. This includes molecular barcodes, termed “mass tags” that enable sample multiplexing, as well as computational approaches for increasing the sensitivity of protein analysis. We aim to apply these advances in societally-relevant areas, with a specific focus on neurodegenerative disease. To do so, we are collaborating with leaders in neurodegenerative disease from around the world. To learn more about PTI’s approach for studying neurodegenerative disease, please visit this page. To learn more about our technology for increasing the throughput of protein analysis, please visit here.
Researchers at PTI have the opportunity to work within an interdisciplinary team of mass spectrometrists, chemists, computational analysts, and biologists to push the boundaries of protein analysis. PTI supports professional development through educational opportunities such as travel to conferences workshops.
Members of PTI receive industry-level resources to lead research projects and have the opportunity to disseminate their discoveries and innovations through high-visibility publications, presentations, and submissions to public data portals.
","descriptionBodyPlain":"Parallel Squared Technology Institute (PTI) is a non-profit research institute developing technologies, reagents, and computational tools to increase the sensitivity and throughput of protein analysis, with a specific focus on single-cell proteomics. We are applying these innovations to societally-relevant areas of biomedical research. As part of these efforts, we are developing new approaches to study protein dysfunctions in Alzheimer’s and related neurodegenerative diseases.\n\nSummary of Position\nWe are seeking scientist and senior scientist candidates to help drive our efforts to use single-cell proteomics to understand the causes of Alzheimer’s and related neurodegenerative diseases. Ideal candidates will have expertise in the molecular mechanisms of neurodegeneration and direct, hand-on experience in single-cell analysis, computational biology, and brain tissue handling. \n\nCandidates will have the opportunity to work as part of an interdisciplinary team in multiple areas, including on NIH-funded projects, using proteomic technologies developed at PTI to discover new molecular mechanisms of neurodegeneration in Alzheimer’s and related disorders. Day-to-day responsibilities include designing and carrying out experiments to isolate and profile single cells from brain tissue, computationally analyzing large-scale single-cell proteomics datasets, preparing manuscripts and presentations, mentoring junior scientists, and regular meetings with collaborators in and outside of PTI. Candidates will initially work on ongoing projects but will have the opportunity to design and lead their own projects as well. \n\nCandidates with less than 1 year of postdoctoral experience will be considered for the scientist position and those with more than 1 year of experience will be considered for the senior scientist position. \n\nAbout PTI\nPTI is a nonprofit, focused research organization (FRO) established through Convergent Research. FROs aim to accelerate progress across science and technology by tackling large-scale problems with the potential to unlock existing bottlenecks in specific research areas. PTI aims to achieve a 100-1000x increase in the scale of proteomic analysis. To do so, we are developing new technologies and approaches for mass spectrometric proteomics. This includes molecular barcodes, termed “mass tags” that enable sample multiplexing, as well as computational approaches for increasing the sensitivity of protein analysis. We aim to apply these advances in societally-relevant areas, with a specific focus on neurodegenerative disease. To do so, we are collaborating with leaders in neurodegenerative disease from around the world. To learn more about PTI’s approach for studying neurodegenerative disease, please visit this page. To learn more about our technology for increasing the throughput of protein analysis, please visit here. \n\nResearchers at PTI have the opportunity to work within an interdisciplinary team of mass spectrometrists, chemists, computational analysts, and biologists to push the boundaries of protein analysis. PTI supports professional development through educational opportunities such as travel to conferences workshops. \n\nMembers of PTI receive industry-level resources to lead research projects and have the opportunity to disseminate their discoveries and innovations through high-visibility publications, presentations, and submissions to public data portals. \n","hostedUrl":"https://jobs.lever.co/convergentresearch/82540c08-47ab-457a-bc22-f9abf5e0c427","applyUrl":"https://jobs.lever.co/convergentresearch/82540c08-47ab-457a-bc22-f9abf5e0c427/apply"},{"additionalPlain":"This position is full-time, fixed-term (2 years, with possibility of renewal), subject to funding availability. \n","additional":"This position is full-time, fixed-term (2 years, with possibility of renewal), subject to funding availability.
","categories":{"commitment":"Full Time - Term Limited","department":"[C]worthy","location":"Boulder, CO","team":"[C]worthy","allLocations":["Boulder, CO"]},"createdAt":1781127921976,"descriptionPlain":"About [C]Worthy\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.\n[C]Worthy is headquartered in Boulder, Colorado.\n\nFor full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.\n","description":"About [C]Worthy
\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.
\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.
\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.
\n[C]Worthy is headquartered in Boulder, Colorado.
For full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.
","id":"e62d0373-df49-42f2-ad4d-73d99329d781","lists":[{"text":"Role Overview","content":"We are seeking a Postdoctoral Research Scientist to develop a one-dimensional (1D) OAE process-model testbed within the C-Star modeling system. This lightweight, rapidly iterable modeling environment is designed to isolate and characterize the biogeochemical processes most critical to OAE efficacy in the vicinity of alkalinity addition: mineral particulate dissolution and precipitation kinetics, particle transport and sinking, electrochemical alkalinity addition, and sediment alkalinity cycling. The processes identified by the 1D testbed will enable increasing skill and confidence in estimates of total alkalinity delivery into the regional-scale water column, and act as a tool for uncertainty characterization. The resulting parameterizations will feed directly into three-dimensional ROMS-MARBL regional model configurations—ensuring that scientific advances made in the testbed translate immediately into improved operational MRV tools across [C]Worthy's full modeling stack.
\n
This project addresses a fundamental bottleneck in OAE science: the mismatch between the complexity of the relevant biogeochemical processes and the computational cost of resolving them in full 3D ocean simulations. The 1D testbed eliminates that mismatch, enabling rapid parameter sweeps, systematic perturbed-parameter ensembles, and clean comparison against laboratory and field datasets. The work proceeds in close collaboration with industry partners including Ebb Carbon, Planetary, and Isometric, who will contribute empirical constraints from field and laboratory deployments.
"},{"text":"Key Responsibilities","content":"\n
Testbed Development and Scientific Investigation
\n\n
\nDesign and implement a one-dimensional OAE process-model testbed within C-Star, using a lightweight physical solution (idealized mixing, turbulence, lateral flows) that allows rapid model prototyping and iteration.
\n\n
\nDevelop a generalized representation of explicitly sinking particulate material within the MARBL biogeochemical model, including parameterizations of mineral dissolution (e.g., olivine, calcite), precipitation kinetics, and particle sinking velocities.
\n\n
\nDevelop and calibrate representations of particles generated in situ by electrochemical and mineral alkalinity addition, in collaboration with industry and other research partners.
\n\n
\nRun large perturbed-parameter ensembles to systematically explore parameter space and quantitatively assess uncertainty in OAE-relevant outcomes.
\n\n
\nValidate parameterizations against existing empirical datasets from laboratory experiments and field deployments, in close collaboration with Ebb Carbon, Planetary Technologies and other partners.
\n\n
\nDevelop and/or implement a simplified model of alkalinity cycling in seafloor sediments, characterizing the level of sediment process representation required for robust OAE simulation at regional scales.
\n\n\n
Integration and Infrastructure
\n\n
\nImplement all process formulations within the ROMS-MARBL framework so that validated parameterizations are immediately portable to three-dimensional C-Star configurations.
\n\n
\nContribute to C-Star software infrastructure, ensuring the testbed is a first-class C-Star component with proper blueprint and workplan schema, documentation, and reproducibility.
\n\n
\nDevelop tutorials and demonstrations for how to use the testbed to develop and improve OAE-related parameterizations—supporting the broader research community's ability to contribute process advances.
\n\n\n
Scientific Communication and Collaboration
\n\n
\nMaintain active, substantive collaboration with Ebb Carbon, Planetary Technology, Isometric, and other partners to ensure model development is grounded in practical implementation and observational reality.
\n\n
\nSubmit peer-reviewed manuscripts documenting parameterization calibration, validation, and scientific findings.
\n\n
\nContribute to [C]Worthy's broader scientific program, including participation in field-building, user roundtables, and community engagement.
\n\n\n
\n\n
\nPh.D. in oceanography, marine chemistry, geochemistry, chemical oceanography, or a closely related field.
\n\n
\nStrong background in ocean biogeochemistry, including carbonate chemistry, alkalinity, and marine carbon cycling.
\n\n
\nFamiliarity with marine mineral dissolution/precipitation kinetics and/or particle dynamics.
\n\n
\nScientific software development proficiency in Python; experience working with biogeochemical model code (Python, Fortran, or Julia).
\n\n
\nAbility to design systematic numerical experiments, interpret results in light of observational constraints, and communicate findings clearly.
\n\n
\nCollaborative disposition and comfort working in partnership with industry stakeholders alongside academic researchers.
\n\n\n
About [C]Worthy
\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.
\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.
\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.
\n[C]Worthy is headquartered in Boulder, Colorado.
For full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.
","descriptionBodyPlain":"About [C]Worthy\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.\n[C]Worthy is headquartered in Boulder, Colorado.\n\nFor full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/e62d0373-df49-42f2-ad4d-73d99329d781","applyUrl":"https://jobs.lever.co/convergentresearch/e62d0373-df49-42f2-ad4d-73d99329d781/apply"},{"additionalPlain":"This position is full-time, fixed-term (2 years, with possibility of renewal). We expect this role to start in the Fall (September, 2026).\n","additional":"This position is full-time, fixed-term (2 years, with possibility of renewal). We expect this role to start in the Fall (September, 2026).
","categories":{"commitment":"Full Time - Term Limited","department":"[C]worthy","location":"Boulder, CO","team":"[C]worthy","allLocations":["Boulder, CO"]},"createdAt":1781128274292,"descriptionPlain":"About [C]Worthy\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.\n \nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.\n \nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.\n \n[C]Worthy is headquartered in Boulder, Colorado.\n\nFor full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.\n","description":"About [C]Worthy
\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.
\n
\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.
\n
\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.
\n
\n[C]Worthy is headquartered in Boulder, Colorado.
For full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.
","id":"07147ace-4d67-47de-9a0a-c7add68bbb68","lists":[{"text":"Role Overview","content":"We are seeking a Postdoctoral Research Scientist to work with our team on the development of a high-resolution Ocean CDR Atlas dataset for the West Coast of North America. This dataset will provide a library of uptake efficiency kernels enabling MRV quantification for OAE deployments across the eastern Pacific without requiring new model runs for each scenario—dramatically lowering the modeling burden for individual project MRV and providing a broadly accessible reference for market standards, accounting frameworks, permitting and regulatory decision making, public communication, and research applications.
\n
\nThe Atlas simulations will be performed with the ROMS-MARBL regional ocean model within C-Star. The postdoc will configure and validate a mesoscale-resolving domain spanning the Eastern Pacific, co-design a nested submesoscale-resolving subdomain with external collaborators, run targeted sensitivity experiments, and aid in the release the Atlas as a public, fully documented dataset with reproducible C-Star workflows.
"},{"text":"Key Responsibilities","content":"Regional Modeling and Atlas Generation
\n\n\nConfigure a mesoscale-resolving ROMS-MARBL domain for the West Coast of North America within C-Star; establish baseline model performance and validation benchmarks.
\n\n\nValidate the CDR Tracer (two-tracer) framework within the regional configuration; confirm fidelity against full MARBL reference simulations.
\n\n\nDesign and execute targeted sensitivity experiments addressing geographic release season and location, surface vs. bottom-intensified release configurations, and submesoscale resolution sensitivity.
\n\n\nCo-design and configure a nested submesoscale-resolving subdomain (in collaboration with external partners) to examine mixed-layer exchange dynamics at 1–10 km scales.
\n\n\nDevelop derived data products using linear superposition of OAE and DOR signals to support multi-intervention simulations (ERW, riverine alkalinity enhancement, partially equilibrated OAE).
\n\n\nReproducible Workflows and Data Release
\n\n\nManage production runs under the resulting HPC allocation.
\n\n\nBuild reproducible, documented dataset-generation workflows within C-Star that are extensible to other regions and serve as templates for future Atlas projects.
\n\n\nWork with the larger team to:
\n\n\ndesign and implement a data formatting, transformation, and management strategy;
\n\n\ndesign and implement a public data hosting strategy, including example analysis tools;
\n\n\nand release the Atlas as a public, documented dataset with an uptake efficiency kernel library enabling convolution-based MRV for arbitrary deployment configurations.
\n\n\n\n\nCommunity Engagement and Scientific Communication
\n\n\nWork with the larger team to actively engage the data user community — including CDR deployment operators, MRV practitioners, and academic collaborators — through direct outreach, workshops, and/or collaborative design.
\n\n\nSubmit a peer-reviewed manuscript documenting methodology, validation, and key scientific results.
\n\n\nContribute to [C]Worthy's broader scientific program, including participation in field-building activities, user roundtables, and community engagement.
\n\n"},{"text":"Required Qualifications","content":"\nPh.D. in oceanography, atmospheric science, geophysical fluid dynamics, or a closely related field.\nDemonstrated experience configuring, running, and evaluating regional ocean models (ROMS, MOM6, NEMO, FVCOM, or equivalent).\nStrong background in ocean biogeochemistry, including carbonate chemistry and air-sea gas exchange.\nScientific software development proficiency in Python; ability to work with large geospatial datasets.\nExperience with HPC computing environments (e.g., NERSC, NCAR/Wyoming, NSF ACCESS).\nAbility to independently design and execute model experiments and interpret results in the context of real-world applications.\nStrong written and oral communication skills; ability to collaborate in a small, fast-moving research team.\n"},{"text":"Preferred Qualifications","content":"\nFamiliarity with ROMS or MARBL source code; experience with coupled physical-biogeochemical model configuration.\nPrior work on CDR quantification, MRV methodology, or ocean carbon cycle research.\nExperience developing reproducible scientific workflows (e.g., Prefect, Snakemake, or similar orchestration tools).\nFamiliarity with data formats designed for large, cloud-native, multi-dimensional spatial data (e.g. ZARR, HDF, netCDF, COG), visualization tools, and public dataset publication practices.\nExperience engaging with non-academic stakeholders (industry, policy, NGOs) or contributing to applied science products.\nInterest in and familiarity with AI/ML approaches as applied to scientific modeling or data analysis.\n"}],"salaryRange":{"min":83000,"max":95000,"currency":"USD","interval":"per-year-salary"},"text":"Postdoctoral Research Scientist, Ocean CDR Atlas","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"About [C]Worthy
\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.
\n
\nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.
\n
\nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.
\n
\n[C]Worthy is headquartered in Boulder, Colorado.
For full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.
","descriptionBodyPlain":"About [C]Worthy\n[C]Worthy is a non-profit research organization focused on transforming research-grade oceanographic models into open, reproducible, and auditable decision-support tools for ocean-based carbon dioxide removal (CDR). Our mission is to deliver trustworthy, science-backed tools for Monitoring, Reporting, and Verification (MRV)—enabling governments, communities, and markets to make high-stakes ocean decisions grounded in transparent, scientifically credible evidence.\n \nWe are building three interlocking open-science capabilities: C-Star, an open-source modeling platform that systematizes regional ocean model configuration, execution, and evaluation through versioned inputs, automated workflows, and comprehensive provenance tracking; the C-Star Ocean Network (C-SON), a growing constellation of standardized regional modeling domains designed to support consistent CDR accounting across sites and regions; and the Ocean CDR Atlas, an open dataset library and web tools that map CDR performance, connectivity, and risk drivers across ocean regions—providing the basis for low-cost MRV evaluation and standard-setting worldwide.\n \nThese capabilities are not CDR tools alone—they are the foundation for scalable ocean science. Robust shared infrastructure makes knowledge transferable and auditable: once validated domains, standardized workflows, and reusable tooling are in place, the marginal cost of each additional application falls and the benefits of research innovation can flow across a network of projects and regions. We aspire to democratize access to sophisticated ocean information tools, empowering diverse scientific communities to participate in ocean governance and marine resource management on their own terms.\n \n[C]Worthy is headquartered in Boulder, Colorado.\n\nFor full consideration, please apply by June 30, 2026. Applications received after this date will be reviewed on a rolling basis until the position is filled.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/07147ace-4d67-47de-9a0a-c7add68bbb68","applyUrl":"https://jobs.lever.co/convergentresearch/07147ace-4d67-47de-9a0a-c7add68bbb68/apply"},{"additionalPlain":"\n\n\nWe aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.\n \nWe are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.","additional":"
We aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"department":"Parallel Squared Technology Institute","location":"Watertown, MA","team":"PTI","allLocations":["Watertown, MA"]},"createdAt":1732118194405,"descriptionPlain":"Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.\n\nWhy? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.\n\nHow? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.\n\nWho? PTI’s new approach requires synergy between a diverse team of chemists, machine learning engineers, biologists and mass spectrometrists. Alzheimer’s disease and aging will be among the first focuses of this technology-driven research organization.\n\nNew career opportunities\nMembers of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals. \n","description":"Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.
Why? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.
How? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.
Who? PTI’s new approach requires synergy between a diverse team of chemists, machine learning engineers, biologists and mass spectrometrists. Alzheimer’s disease and aging will be among the first focuses of this technology-driven research organization.
New career opportunities
Members of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals.
","id":"29856337-1a89-455a-a59d-e6b261bd1856","lists":[{"text":"Qualifications we are generally interested in for different roles:","content":"Master’s or PhD in Computational Biology, Bioinformatics, Bioengineering, Molecular Biology, Neurobiology, or related field. BS degree with at least 3 years of experience are also welcome to apply.Experience with LC-MS/MS, particularly for proteomics.Able to develop highly-sensitive workflows for data acquisition by LC-MS/MS pipelines.Experience collaborating with biologists, chemists, research associates, computational scientists, and mass spectrometrists to leverage PTI's multiplexing platform.Experience in large-scale analyses that involve many samples, such as thousands of single cells or bulk tissues, and then visualizing datasets with Python and/or R as well as the command line.Reproducible research using tools such as git, Jupyter notebooks, etc.Experience with cloud environments such as AWS or Google Cloud. Preparation and analysis of brain samples, or equivalent working experience. In particular, preparing human brain tissue for downstream protein analyses. Mentoring scientists and research associates. Preparing internal reports and manuscripts, and presenting results at internal or external scientific meetings as appropriate.Demonstrable commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others."},{"text":"We offer:","content":"An opportunity to change the world and work with some of the smartest and the most talented experts from different fields.Excellent medical, dental, and vision insurance with many $0 premium options for you and your family with several national and regional providers. Most employees have more than 20 plan options to choose from.Company-paid group life, AD&D, long- and short-term disability insurance15 days PTO + 10 sick days per year18 company holidays + your birthday off$5,000 per year educational reimbursementUp to 16 weeks paid parental leave"}],"text":"Potentially a good fit for PTI?","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.
Why? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.
How? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.
Who? PTI’s new approach requires synergy between a diverse team of chemists, machine learning engineers, biologists and mass spectrometrists. Alzheimer’s disease and aging will be among the first focuses of this technology-driven research organization.
New career opportunities
Members of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals.
","descriptionBodyPlain":"Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.\n\nWhy? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.\n\nHow? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.\n\nWho? PTI’s new approach requires synergy between a diverse team of chemists, machine learning engineers, biologists and mass spectrometrists. Alzheimer’s disease and aging will be among the first focuses of this technology-driven research organization.\n\nNew career opportunities\nMembers of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals. \n","hostedUrl":"https://jobs.lever.co/convergentresearch/29856337-1a89-455a-a59d-e6b261bd1856","applyUrl":"https://jobs.lever.co/convergentresearch/29856337-1a89-455a-a59d-e6b261bd1856/apply"},{"additionalPlain":"\n\n\nWe aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.\n \nWe are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.","additional":"
We aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","categories":{"commitment":"Full Time","department":"[C]worthy","location":"Boulder, CO","team":"[C]worthy","allLocations":["Boulder, CO"]},"createdAt":1691623989836,"descriptionPlain":"[C]Worthy is a non-profit research organization building the first open-source software and analytics tools designed to enable trustworthy, transparent, science-based quantification of ocean-based carbon removal. We are working to help the growing mCDR industry make safe and effective long-term contributions to climate change mitigation. \n\nThe [C]Worthy research and development team blends exceptional software engineering with deep expertise in oceanographic observations, modeling, and data assimilation. [C]Worthy is on the path to becoming a Convergent Research focused research organization. We are located in Boulder, Colorado. \n\nIf you are passionate about using your skills to help tackle the climate crisis, think you may be a great fit for [C]Worthy, but don’t see a role which looks tailored to you – we encourage you to apply to our general applicant pool. We routinely review resumes/CVs submitted through this channel.\n","description":"[C]Worthy is a non-profit research organization building the first open-source software and analytics tools designed to enable trustworthy, transparent, science-based quantification of ocean-based carbon removal. We are working to help the growing mCDR industry make safe and effective long-term contributions to climate change mitigation.
The [C]Worthy research and development team blends exceptional software engineering with deep expertise in oceanographic observations, modeling, and data assimilation. [C]Worthy is on the path to becoming a Convergent Research focused research organization. We are located in Boulder, Colorado.
If you are passionate about using your skills to help tackle the climate crisis, think you may be a great fit for [C]Worthy, but don’t see a role which looks tailored to you – we encourage you to apply to our general applicant pool. We routinely review resumes/CVs submitted through this channel.
","id":"98fe2da8-88d4-46e3-b2e4-5c6559f974c8","lists":[{"text":"Some example roles that we are looking to fill in the next year","content":"BiogeochemistCoastal or regional ocean modelerSoftware engineer (scientific, dev-ops, cloud HPC) Technical project manager Operations managerData scientist/data engineer (stats, ML/AI, etc) "},{"text":"People who will love working at [C]Worthy are","content":"Excited to be involved in the emerging ocean CDR industryDeeply curious and love to learn new thingsCollaborative, helpful, open-minded, and willing to listen to other’s perspectivesOpen to admitting mistakesTenacious and adaptive problem-solversLooking for a chance to enjoy themselves at work! "},{"text":"Benefits","content":"Benefits include health, vision, and dental insurance A wellness benefitPaid time offFlexible spending accounts for health care or childcareA 401(k) retirement fund with matching employer contributions"},{"text":"Location ","content":"[C]Worthy is based in Boulder, Colorado, and seeks to build a strong collaborative team. We prefer that employees spend significant time working together in person in our Boulder office, however approval for remote or hybrid work is possible. "}],"text":"Potentially a great fit for [C]Worthy?","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"[C]Worthy is a non-profit research organization building the first open-source software and analytics tools designed to enable trustworthy, transparent, science-based quantification of ocean-based carbon removal. We are working to help the growing mCDR industry make safe and effective long-term contributions to climate change mitigation.
The [C]Worthy research and development team blends exceptional software engineering with deep expertise in oceanographic observations, modeling, and data assimilation. [C]Worthy is on the path to becoming a Convergent Research focused research organization. We are located in Boulder, Colorado.
If you are passionate about using your skills to help tackle the climate crisis, think you may be a great fit for [C]Worthy, but don’t see a role which looks tailored to you – we encourage you to apply to our general applicant pool. We routinely review resumes/CVs submitted through this channel.
","descriptionBodyPlain":"[C]Worthy is a non-profit research organization building the first open-source software and analytics tools designed to enable trustworthy, transparent, science-based quantification of ocean-based carbon removal. We are working to help the growing mCDR industry make safe and effective long-term contributions to climate change mitigation. \n\nThe [C]Worthy research and development team blends exceptional software engineering with deep expertise in oceanographic observations, modeling, and data assimilation. [C]Worthy is on the path to becoming a Convergent Research focused research organization. We are located in Boulder, Colorado. \n\nIf you are passionate about using your skills to help tackle the climate crisis, think you may be a great fit for [C]Worthy, but don’t see a role which looks tailored to you – we encourage you to apply to our general applicant pool. We routinely review resumes/CVs submitted through this channel.\n","hostedUrl":"https://jobs.lever.co/convergentresearch/98fe2da8-88d4-46e3-b2e4-5c6559f974c8","applyUrl":"https://jobs.lever.co/convergentresearch/98fe2da8-88d4-46e3-b2e4-5c6559f974c8/apply"},{"additionalPlain":"Melody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.\n","additional":"\n
Melody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
\n
\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
\n
About the role: we are hiring a protein engineer to create new biosensors composed of allosteric switches, signal transduction motifs (e.g., linkers), reporter proteins, site-specific chemical modifications, and bioelectronic interfaces. The engineer will design new constructs, guide wet lab screening, and work with the hardware team to select performant constructs. You will also mentor and manage junior scientists and work with Melody’s outside academic collaborators and CRO partners.
\n
You may excel in this role if you enjoy creating new molecules from scratch and working with target product profiles. Ideal candidates will be able to manage both open-ended searches in protein space while working with the engineering team on performance optimization.
\n
What success looks like:
\n
In 3 months - set up de novo design and directed evolution workflows for our foundry.
\n
In 6 months - design and validate your own biosensor scaffolds against ions, small molecules, and peptides.
\n
In 15 months - integrate experimental feedback from devices and revamp design workflow.
\n
Required Qualifications:
\n
\n- \n
Strength in one self-identified track: (a) experimental-first - where your strengths and approaches rely on mining naturally occurring motifs, using chemical intuition to design sensors, and experimental testing to effectively select candidates OR (b) computation-first where your strengths and approaches rely on de novo design methods (reducing the number and breadth of experimental loops).
\n \n- \n
Structural biology and biophysics competency related to optical and electrophysiological measurements.
\n \n- \n
PhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).
\n \n- \n
Quantitative judgment for designing experiments under real-world constraints, matching roadmap goals to instrument capabilities and lab throughput.
\n \n- \n
Demonstrated precision in experimental work and scientific project management.
\n \n- \n
Strong technical communication skills across the relevant scientific fields and teams.
\n \n
\n
Preferred Qualifications:
\n
\n- \n
3+ years industry experience in protein design and selection.
\n \n- \n
Ability to write custom scripts for data analysis and interfacing with lab instruments.
\n \n- \n
Working ability in both experimental methods and computational tools for protein design.
\n \n- \n
Conceptual command of allostery and protein dynamics.
\n \n- \n
Conceptual command of the electronic nose field.
\n \n- \n
2+ years of team management and mentoring experience. We are especially interested in those with a track record of coordinating across chemists, materials scientists, hardware engineers, software/data scientists, vendors, and academic collaborators.
\n \n
\n
\n
Salary leveled based on experience, fit, and assignment to computational- or experiment-first track.
\n
We offer:
\n
401k match up to 6% of base salary.
\n
Excellent health, vision, and dental benefits.
\n
Paid time off and company holidays.
\n
\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
\n
About the role: we are hiring a protein engineer to create new biosensors composed of allosteric switches, signal transduction motifs (e.g., linkers), reporter proteins, site-specific chemical modifications, and bioelectronic interfaces. The engineer will design new constructs, guide wet lab screening, and work with the hardware team to select performant constructs. You will also mentor and manage junior scientists and work with Melody’s outside academic collaborators and CRO partners.
\n
You may excel in this role if you enjoy creating new molecules from scratch and working with target product profiles. Ideal candidates will be able to manage both open-ended searches in protein space while working with the engineering team on performance optimization.
\n
What success looks like:
\n
In 3 months - set up de novo design and directed evolution workflows for our foundry.
\n
In 6 months - design and validate your own biosensor scaffolds against ions, small molecules, and peptides.
\n
In 15 months - integrate experimental feedback from devices and revamp design workflow.
\n
Required Qualifications:
\n
\n- \n
Strength in one self-identified track: (a) experimental-first - where your strengths and approaches rely on mining naturally occurring motifs, using chemical intuition to design sensors, and experimental testing to effectively select candidates OR (b) computation-first where your strengths and approaches rely on de novo design methods (reducing the number and breadth of experimental loops).
\n \n- \n
Structural biology and biophysics competency related to optical and electrophysiological measurements.
\n \n- \n
PhD in a relevant science and engineering field with demonstrated strong independent ideation and execution or BS/MS with extensive industry experience (> 5 years).
\n \n- \n
Quantitative judgment for designing experiments under real-world constraints, matching roadmap goals to instrument capabilities and lab throughput.
\n \n- \n
Demonstrated precision in experimental work and scientific project management.
\n \n- \n
Strong technical communication skills across the relevant scientific fields and teams.
\n \n
\n
Preferred Qualifications:
\n
\n- \n
3+ years industry experience in protein design and selection.
\n \n- \n
Ability to write custom scripts for data analysis and interfacing with lab instruments.
\n \n- \n
Working ability in both experimental methods and computational tools for protein design.
\n \n- \n
Conceptual command of allostery and protein dynamics.
\n \n- \n
Conceptual command of the electronic nose field.
\n \n- \n
2+ years of team management and mentoring experience. We are especially interested in those with a track record of coordinating across chemists, materials scientists, hardware engineers, software/data scientists, vendors, and academic collaborators.
\n \n
\n
\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
About the role: we are hiring a Research Associate to work with the scientific team to build and run Melody’s bioelectronics foundry. You will be responsible for evolving and testing new protein biosensors. Your work will involve molecular biology, liquid handling robotics, and novel hardware developed by the team for running biophysical assays. You will work closely with the chemistry and device engineering teams to move biosensor candidates from DNA constructs to purified proteins, screening data, device-relevant assays, and quantitative performance measurements.
\n
You may excel in this role if you enjoy using an engineering mindset in wet lab biology, developing an intuition of how proteins behave from hands-on work, and working in a team-setting to pioneer new methods. Specifically you will:
\n
\n- Express and purify engineered binders and biosensors.
\n- Design, order, and prepare DNA constructs, mutant libraries, and binder-reporter variants.
\n- Run fluorescence, plate-reader, biochemical, biophysical, and novel device-based assays.
\n- Generate dose-response curves and quantify EC50/Kd, dynamic range, signal-to-noise, selectivity, kinetics, reversibility, stability, and drift.
\n- Support yeast display, FACS-based screening, and directed evolution workflows.
\n- Interface biosensors with optical and electrochemical readouts on benchtop hardware.
\n- Help automate assay workflows using liquid handlers, plate readers, and custom scripts.
\n- Maintain clean records of constructs, samples, sequence-function relationships, assay metadata, instrument settings, and experimental results.
\n- Collaborate with scientists and engineers to turn one-off assays into repeatable workflows that scale to the needs of the platform.
\n
\n
Required Qualifications:
\n
\n- BA or BS in biology, chemistry, physics or other relevant field.
\n- 2+ years experience in wet lab bench involving protein engineering or biophysical assays.
\n- Demonstrated precision in experimental work and project management.
\n
\n
Preferred Qualifications:
\n- Extensive knowledge of biophysical methods and associated instrumentation for thermodynamics and kinetics measurements.
\n- Ability to write custom scripts in Python/R for data analysis
\n- Experience with lab automation techniques including liquid handling robots.
\n- Experience with biomaterial preparation and protein functionalization chemistry.
\n- Familiarity with industry standards in protein and device engineering.
\n
","id":"209f6b70-cf11-4090-9aaf-96bdab43357e","lists":[],"salaryRange":{"min":65000,"max":95000,"currency":"USD","interval":"per-year-salary"},"salaryDescription":"Salary leveled based on experience and fit.
\n
\nWe offer:
\n\n- 401k match up to 6% of base salary.
\n- Excellent health, vision, and dental benefits.
\n- Paid time off and company holidays.
\n
\n
\nMelody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
","salaryDescriptionPlain":"Salary leveled based on experience and fit. \n \nWe offer:\n401k match up to 6% of base salary.\nExcellent health, vision, and dental benefits.\nPaid time off and company holidays.\n \nMelody FRO, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.\n","text":"Research Associate - Biosensing","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"\n
Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications.
\n
We are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.
\n
About the role: we are hiring a Research Associate to work with the scientific team to build and run Melody’s bioelectronics foundry. You will be responsible for evolving and testing new protein biosensors. Your work will involve molecular biology, liquid handling robotics, and novel hardware developed by the team for running biophysical assays. You will work closely with the chemistry and device engineering teams to move biosensor candidates from DNA constructs to purified proteins, screening data, device-relevant assays, and quantitative performance measurements.
\n
You may excel in this role if you enjoy using an engineering mindset in wet lab biology, developing an intuition of how proteins behave from hands-on work, and working in a team-setting to pioneer new methods. Specifically you will:
\n
\n- Express and purify engineered binders and biosensors.
\n- Design, order, and prepare DNA constructs, mutant libraries, and binder-reporter variants.
\n- Run fluorescence, plate-reader, biochemical, biophysical, and novel device-based assays.
\n- Generate dose-response curves and quantify EC50/Kd, dynamic range, signal-to-noise, selectivity, kinetics, reversibility, stability, and drift.
\n- Support yeast display, FACS-based screening, and directed evolution workflows.
\n- Interface biosensors with optical and electrochemical readouts on benchtop hardware.
\n- Help automate assay workflows using liquid handlers, plate readers, and custom scripts.
\n- Maintain clean records of constructs, samples, sequence-function relationships, assay metadata, instrument settings, and experimental results.
\n- Collaborate with scientists and engineers to turn one-off assays into repeatable workflows that scale to the needs of the platform.
\n
\n
Required Qualifications:
\n
\n- BA or BS in biology, chemistry, physics or other relevant field.
\n- 2+ years experience in wet lab bench involving protein engineering or biophysical assays.
\n- Demonstrated precision in experimental work and project management.
\n
\n
Preferred Qualifications:
\n- Extensive knowledge of biophysical methods and associated instrumentation for thermodynamics and kinetics measurements.
\n- Ability to write custom scripts in Python/R for data analysis
\n- Experience with lab automation techniques including liquid handling robots.
\n- Experience with biomaterial preparation and protein functionalization chemistry.
\n- Familiarity with industry standards in protein and device engineering.
\n
","descriptionBodyPlain":"Melody is an early-stage focused research organization engineering continuous molecular monitoring technology and designing closed-loop interventions for human health. We leverage protein engineering, medical device engineering, and physiology modeling. As a FRO, we uniquely bridge blue-sky science and hardcore manufacturing and pioneer new applications. \nWe are a nonprofit startup based in Pasadena, founded by scientists and engineers from Janelia and Caltech and incubated by Convergent Research. Our goal is to produce public goods: biosensors, devices, datasets, protocols, and tools that help launch a broader field of real-time molecular medicine.\nAbout the role: we are hiring a Research Associate to work with the scientific team to build and run Melody’s bioelectronics foundry. You will be responsible for evolving and testing new protein biosensors. Your work will involve molecular biology, liquid handling robotics, and novel hardware developed by the team for running biophysical assays. You will work closely with the chemistry and device engineering teams to move biosensor candidates from DNA constructs to purified proteins, screening data, device-relevant assays, and quantitative performance measurements.\nYou may excel in this role if you enjoy using an engineering mindset in wet lab biology, developing an intuition of how proteins behave from hands-on work, and working in a team-setting to pioneer new methods. Specifically you will:\nExpress and purify engineered binders and biosensors.\nDesign, order, and prepare DNA constructs, mutant libraries, and binder-reporter variants.\nRun fluorescence, plate-reader, biochemical, biophysical, and novel device-based assays.\nGenerate dose-response curves and quantify EC50/Kd, dynamic range, signal-to-noise, selectivity, kinetics, reversibility, stability, and drift.\nSupport yeast display, FACS-based screening, and directed evolution workflows.\nInterface biosensors with optical and electrochemical readouts on benchtop hardware.\nHelp automate assay workflows using liquid handlers, plate readers, and custom scripts.\nMaintain clean records of constructs, samples, sequence-function relationships, assay metadata, instrument settings, and experimental results.\nCollaborate with scientists and engineers to turn one-off assays into repeatable workflows that scale to the needs of the platform.\nRequired Qualifications:\nBA or BS in biology, chemistry, physics or other relevant field. \n2+ years experience in wet lab bench involving protein engineering or biophysical assays.\nDemonstrated precision in experimental work and project management.\nPreferred Qualifications:\nExtensive knowledge of biophysical methods and associated instrumentation for thermodynamics and kinetics measurements. \nAbility to write custom scripts in Python/R for data analysis\nExperience with lab automation techniques including liquid handling robots.\nExperience with biomaterial preparation and protein functionalization chemistry. \nFamiliarity with industry standards in protein and device engineering. \n","hostedUrl":"https://jobs.lever.co/convergentresearch/209f6b70-cf11-4090-9aaf-96bdab43357e","applyUrl":"https://jobs.lever.co/convergentresearch/209f6b70-cf11-4090-9aaf-96bdab43357e/apply"}]