[{"additional":"","additionalPlain":"","categories":{"commitment":"Contract","department":"Research & Development","location":"Redwood City, CA","team":"Clinical Development","allLocations":["Redwood City, CA"]},"createdAt":1772071949257,"descriptionPlain":"Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is looking to bring on board a Clinical Scientist/Senior (Contract). This role will support the assigned Clinical Trial Lead with the design and execution of key elements of the Clinical Development Plan (clinical study or studies) with minimal to moderate level of supervision. This includes activities relating to study design, data generation and validation and data analysis and interpretation. This individual will be responsible for implementation, planning, and execution of assigned clinical trial activities for one or more trials, co-Leads study team meetings in partnership with clinical operations and collaborates with cross functional study team members. This position may support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning).\n \nContract duration: 6-12 months\n \nNote to Recruiters and Agencies\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.\n","description":"Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is looking to bring on board a Clinical Scientist/Senior (Contract). This role will support the assigned Clinical Trial Lead with the design and execution of key elements of the Clinical Development Plan (clinical study or studies) with minimal to moderate level of supervision. This includes activities relating to study design, data generation and validation and data analysis and interpretation. This individual will be responsible for implementation, planning, and execution of assigned clinical trial activities for one or more trials, co-Leads study team meetings in partnership with clinical operations and collaborates with cross functional study team members. This position may support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning).
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\nContract duration: 6-12 months
\n
\nNote to Recruiters and Agencies
\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
","id":"6daed5bb-f02b-4c81-9d06-f8d944dee5b5","lists":[{"text":"What you'll do: ","content":"\nSupport the design and writing of clinical protocols and associated clinical study documents (e.g., ICFs, charters, operational manuals, etc.)\nServes as an expert on the clinical study design (including trial procedures and requirements) and develops training materials to ensure quality execution by the investigational sites.\nSupport cross-functional teams with study protocol and related questions and serves as point of contact for managing/answering questions relating to trial procedures.\nEngages clinical trial vendors to support study start-up activities in line with the clinical trial design\nProvides medical monitoring support or oversight of activities conducted by a CRO, which includes monitoring, cleaning, analyzing, and reviewing efficacy data to establish the presence or absence of trends and follow up as appropriate\nCollaborate on, or lead where appropriate, the writing of clinical sections of key program documents including Investigational New Drug submissions, Investigator Brochures, Clinical Study Reports, and other global regulatory submissions and responses.\nSupport clinical development planning by participating in the evaluation of innovative trial designs and provisioning and analyzing data from ongoing and/or completed clinical trials to support future planning\nMaintaining awareness of internal and external developments (scientific, clinical, competitive, and regulatory) that could impact the development plan, including attendance at major scientific conferences, participation in competitive intelligence activities, and periodic literature review.\n"},{"text":"About you: ","content":"\nMD, PhD, OD, PharmD with ophthalmology experience, preferably including retina experience required. Gene Therapy experience also preferred.\n5-7 years of experience in a clinical research-related role. 3-5 years' experience in a Clinical science/development role preferred.\nProficient knowledge of GCP/ICH, drug development process, study design, statistics, understanding of functional and cross-functional relationships\nProficient knowledge and skills to support program specific data review, trend identification, data interpretation\nKnowledge of gene and ocular therapies preferred\nKnowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees\nPrevious experience working with CROs and other vendors/suppliers preferred\nPrevious experience with Phase I-III US and Global/Ex-US clinical trials preferred\nExcellent verbal, written, communication and interpersonal skills\nProficient in Medical Terminology and medical writing skills\nProficient critical thinking, problem-solving, decision-making skills\nAdaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism\nProficient in Microsoft Word, Excel, PowerPoint, and general computer use. Experience using Electronic Data Capture (e.g., RAVE), J-Review or similar data reporting tools would be a plus.\n\n
"}],"salaryRange":{"min":70,"currency":"USD","interval":"per-hour-wage","max":80},"salaryDescription":"The hourly range for this position is between $70.00/hr USD to $80.00/hr USD, depending on experience. ","salaryDescriptionPlain":"The hourly range for this position is between $70.00/hr USD to $80.00/hr USD, depending on experience. \n","text":"Clinical Scientist/Senior (Contract)","country":"US","workplaceType":"remote","opening":"","openingPlain":"","descriptionBody":"Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is looking to bring on board a Clinical Scientist/Senior (Contract). This role will support the assigned Clinical Trial Lead with the design and execution of key elements of the Clinical Development Plan (clinical study or studies) with minimal to moderate level of supervision. This includes activities relating to study design, data generation and validation and data analysis and interpretation. This individual will be responsible for implementation, planning, and execution of assigned clinical trial activities for one or more trials, co-Leads study team meetings in partnership with clinical operations and collaborates with cross functional study team members. This position may support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning).
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\nContract duration: 6-12 months
\n
\nNote to Recruiters and Agencies
\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
","descriptionBodyPlain":"Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is looking to bring on board a Clinical Scientist/Senior (Contract). This role will support the assigned Clinical Trial Lead with the design and execution of key elements of the Clinical Development Plan (clinical study or studies) with minimal to moderate level of supervision. This includes activities relating to study design, data generation and validation and data analysis and interpretation. This individual will be responsible for implementation, planning, and execution of assigned clinical trial activities for one or more trials, co-Leads study team meetings in partnership with clinical operations and collaborates with cross functional study team members. This position may support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning).\n \nContract duration: 6-12 months\n \nNote to Recruiters and Agencies\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.\n","hostedUrl":"https://jobs.lever.co/adverum/6daed5bb-f02b-4c81-9d06-f8d944dee5b5","applyUrl":"https://jobs.lever.co/adverum/6daed5bb-f02b-4c81-9d06-f8d944dee5b5/apply"},{"additional":"","additionalPlain":"","categories":{"commitment":"Contract","department":"Research & Development","location":"Redwood City, CA","team":"Quality Control","allLocations":["Redwood City, CA"]},"createdAt":1779991540265,"descriptionPlain":"","description":"\n
Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is a mission-driven clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians’ offices to eliminate the need for frequent ocular injections to treat these diseases. By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
\n
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
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Adverum is seeking a dedicated Quality Control Analyst to be a part of our vibrant team based in our Redwood City office. Reporting variably to the Quality Control Manager, Quality Control Lead, or as a part of a project hierarchy, this role will engage collaboratively with the QC team and other cross-functional teams. As a vital member of the Quality Control unit, the analyst will play a significant role in advancing and performing Quality Control (QC) review of different assay techniques, systems, policies, processes, procedures, and controls pertinent to the analytical examination of clinical materials.
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Review, analyze, and verify analytical data for drug substance and finished product testing, ensuring accuracy, completeness, reliability, and data integrity.
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Provide technical expertise in the review of analytical methods, assay execution, and troubleshooting activities within the QC laboratory, with particular focus on qPCR, Potency, ELISA, SEC and related techniques.
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Review and follow SOPs, test methods, specifications, and controlled documents; support the revision and continuous improvement of QC procedures to maintain compliance.
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Review completed testing records, sample documentation, and final result packages for release, stability, and in-process studies prior to approval.
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Identify, document, and own deviations through closure, including support for investigations, impact assessments, root cause analysis, and corrective actions as needed.
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Support QC investigations, assay lifecycle activities, and nonclinical sample review as needed, collaborating cross-functionally to resolve quality and compliance issues.
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Bachelor’s degree in biology, chemistry, Biochemistry, or a related field, with a minimum of 3-5 years of experience (QC II) or 3-5 years’ experience (QC III), preferable in a bio-pharma analytical laboratory setting
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Proficient in QC review of analytical documentation, including test records, data packages, instrument printouts, and associated documentation generated from systems such as Empower, SoftMax Pro and related laboratory software.
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Experience reviewing analytical methods, raw data, and supporting documentation for techniques such as Potency, qPCR, SEC, SDS-PAGE, DLS, and similar assays in a regulated laboratory environment.
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Experience in quality control documentation review is required based on level, with a strong understanding of compliance expectations, good documentation practices, and analytical record assessment; a solid foundation in molecular biology is desired.
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Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is a mission-driven clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians’ offices to eliminate the need for frequent ocular injections to treat these diseases. By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
\n
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
\n
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Adverum is seeking a dedicated Quality Control Analyst to be a part of our vibrant team based in our Redwood City office. Reporting variably to the Quality Control Manager, Quality Control Lead, or as a part of a project hierarchy, this role will engage collaboratively with the QC team and other cross-functional teams. As a vital member of the Quality Control unit, the analyst will play a significant role in advancing and performing Quality Control (QC) review of different assay techniques, systems, policies, processes, procedures, and controls pertinent to the analytical examination of clinical materials.
\n
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Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.
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At Adverum, Inclusion and Diversity are at our core. We believe in the power of being your authentic self. We strive to create the space which allows for everyone in our Adverum Community to not only feel safe but encouraged to speak, learn from each other, grow in their professions and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation
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\n
Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is a mission-driven clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians’ offices to eliminate the need for frequent ocular injections to treat these diseases. By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
\n
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
\n
Adverum is looking for a Senior Scientist, Downstream Process Development to join the Process Development team at our Redwood City, CA office. The individual will be part of the team responsible for developing and optimizing the downstream process development activities for adeno-associated virus (AAV) gene therapy programs. The successful candidate will participate in late-stage activities including design and optimization of the process as needed using historical batch data and manufacturing needs; process characterization; and tech-transfer of downstream processes to support clinical and commercial manufacturing. This role requires a deep understanding of chromatography, filtration, and gene therapy-specific challenges in AAV vector production, as well as experience in transitioning processes to GMP-compliant manufacturing. This position is onsite 5 days a week.
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Support late‑stage AAV downstream process development and optimization to ensure scalability, robustness, reproducibility, and regulatory compliance.\nLead and execute purification development, including chromatography (AFF, IEX) and filtration (depth, NFF, TFF).\nIndividually and partner with other SMEs to author protocols and reports, and execute on process characterization and validation studies (FMEA, scale‑down models, DOE/OFAT, PPQ, hold studies).\nCompile and analyze process and analytical data in Excel, JMP, or similar software, to identify trends, drive optimization, and lead and support investigations / RCA.\nPresent study findings, issues, and trends to PD and cross-functional CMC teams.\nSupport downstream material generation team as needed to maintain company timelines.\nDownstream SME to support external manufacturing operations including technical meetings, BPR and related records review, execution, and troubleshooting.\nCollaborate cross‑functionally (AD, USP, QC, RA) to ensure seamless transition from development to commercial.\nProvide line leadership if needed.\nAuthor/review technical documentation (development reports, SOPs, CMC sections for regulatory filings, Process Monitoring and Control Strategies).\nStay updated on industry trends and emerging technologies in gene therapy manufacturing to maintain best-in-class process development practices.\n\n"},{"text":"About You:","content":"\n
\n- Ph.D. in Biochemistry, Chemical Engineering, Molecular Biology, or related field with 4-6+ years of relevant experience in downstream process development; or M.S. with 8+ years of experience.
\n- Proven experience in AAV or other viral vector production, preferably in late-stage development for clinical/commercial scale manufacturing.
\n- Strong expertise and in-depth knowledge in functioning and troubleshooting of purification process development/manufacturing equipment such as chromatography and filtration systems.
\n- Experience with scalable, AKTA, depth filtration, and TFF systems.
\n- Knowledge of GMP requirements and regulatory guidelines for gene therapy products.
\n- Prefer to have knowledge of DOE principles, process characterization, and BLA enabling activities.
\n- Background in authoring sections of regulatory submissions, including IND, or BLA filings.
\n- Excellent problem-solving skills with the ability to troubleshoot and optimize complex bioprocesses.
\n- Strong communication and leadership skills to manage cross-functional projects and mentor team members.
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Adverum Biotechnologies, Inc., wholly owned subsidiary of Eli Lilly and Company, is a mission-driven clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians’ offices to eliminate the need for frequent ocular injections to treat these diseases. By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
\n
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered Adverum's property. Adverum’s Talent Acquisition team must expressly engage agencies for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
\n
Adverum is looking for a Senior Scientist, Downstream Process Development to join the Process Development team at our Redwood City, CA office. The individual will be part of the team responsible for developing and optimizing the downstream process development activities for adeno-associated virus (AAV) gene therapy programs. The successful candidate will participate in late-stage activities including design and optimization of the process as needed using historical batch data and manufacturing needs; process characterization; and tech-transfer of downstream processes to support clinical and commercial manufacturing. This role requires a deep understanding of chromatography, filtration, and gene therapy-specific challenges in AAV vector production, as well as experience in transitioning processes to GMP-compliant manufacturing. This position is onsite 5 days a week.
\n
At Adverum, Inclusion and Diversity are at our core. We believe in the power of being your authentic self. We strive to create the space that allows for everyone in our Adverum Community to not only feel safe but also encouraged to speak, learn from each other, grow in their professions, and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation.
","categories":{"commitment":"Full Time","location":"Redwood City, CA","team":"Role not posted","allLocations":["Redwood City, CA"]},"createdAt":1603989054204,"descriptionPlain":"Adverum is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the capabilities of its proprietary intravitreal platform, Adverum is developing durable, single-administration therapies, designed to be delivered in physicians’ offices, to eliminate the need for frequent ocular injections to treat these diseases. Adverum is evaluating its novel gene therapy candidate, ixoberogene soroparvovec (Ixo-vec), as a one-time, IVT injection for patients with neovascular or wet age-related macular degeneration. Additionally, by overcoming the challenges associated with current treatment paradigms for debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.\n\nNote to Recruiters and Agencies\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered property of Adverum. Agencies must be expressly engaged by Adverum’s Talent Acquisition team for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.\n\n\n\nAt Adverum, we’re always excited to meet people who share our mission. If you don’t see a role that fits today, share your details—we’re always looking to connect with those who believe that great science starts with great people. \n","description":"Adverum is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the capabilities of its proprietary intravitreal platform, Adverum is developing durable, single-administration therapies, designed to be delivered in physicians’ offices, to eliminate the need for frequent ocular injections to treat these diseases. Adverum is evaluating its novel gene therapy candidate, ixoberogene soroparvovec (Ixo-vec), as a one-time, IVT injection for patients with neovascular or wet age-related macular degeneration. Additionally, by overcoming the challenges associated with current treatment paradigms for debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered property of Adverum. Agencies must be expressly engaged by Adverum’s Talent Acquisition team for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
At Adverum, we’re always excited to meet people who share our mission. If you don’t see a role that fits today, share your details—we’re always looking to connect with those who believe that great science starts with great people.
","id":"2a92e0c0-4a8d-44f0-b039-25d4d27fda94","lists":[],"salaryRange":{"min":0,"max":0,"currency":"USD","interval":"bi-week-salary"},"text":"Work with us!","country":"US","workplaceType":"hybrid","opening":"Adverum is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the capabilities of its proprietary intravitreal platform, Adverum is developing durable, single-administration therapies, designed to be delivered in physicians’ offices, to eliminate the need for frequent ocular injections to treat these diseases. Adverum is evaluating its novel gene therapy candidate, ixoberogene soroparvovec (Ixo-vec), as a one-time, IVT injection for patients with neovascular or wet age-related macular degeneration. Additionally, by overcoming the challenges associated with current treatment paradigms for debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.
Note to Recruiters and Agencies
All recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered property of Adverum. Agencies must be expressly engaged by Adverum’s Talent Acquisition team for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.
","openingPlain":"Adverum is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the capabilities of its proprietary intravitreal platform, Adverum is developing durable, single-administration therapies, designed to be delivered in physicians’ offices, to eliminate the need for frequent ocular injections to treat these diseases. Adverum is evaluating its novel gene therapy candidate, ixoberogene soroparvovec (Ixo-vec), as a one-time, IVT injection for patients with neovascular or wet age-related macular degeneration. Additionally, by overcoming the challenges associated with current treatment paradigms for debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.\n\nNote to Recruiters and Agencies\nAll recruiter and agency inquiries must go through Adverum’s internal Talent Acquisition team. Unsolicited resumes sent to Adverum will be considered property of Adverum. Agencies must be expressly engaged by Adverum’s Talent Acquisition team for any requisition. Direct contact with hiring managers by agencies will not be tolerated and may affect your ability to work with Adverum in the future.\n\n","descriptionBody":"At Adverum, we’re always excited to meet people who share our mission. If you don’t see a role that fits today, share your details—we’re always looking to connect with those who believe that great science starts with great people.
","descriptionBodyPlain":"At Adverum, we’re always excited to meet people who share our mission. If you don’t see a role that fits today, share your details—we’re always looking to connect with those who believe that great science starts with great people. \n","hostedUrl":"https://jobs.lever.co/adverum/2a92e0c0-4a8d-44f0-b039-25d4d27fda94","applyUrl":"https://jobs.lever.co/adverum/2a92e0c0-4a8d-44f0-b039-25d4d27fda94/apply"}]