[{"additionalPlain":"We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.\n\nPlease note that we do not accept unsolicited resumes from recruitment agencies and external recruiters. No fees will be paid for such submissions.\n","additional":"We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
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\nPlease note that we do not accept unsolicited resumes from recruitment agencies and external recruiters. No fees will be paid for such submissions.
","categories":{"commitment":"Contract","department":"4:59 Initiative","location":"Alameda, CA","team":"4:59 - Renasant Bio","allLocations":["Alameda, CA","Berkeley, CA"]},"createdAt":1777316163147,"descriptionPlain":"Company Overview\n\nWe are looking for dedicated professionals who thrive on tackling complex challenges and are committed to improving the lives of patients. If you value innovation, collaboration, and integrity, and are eager to contribute to advancing therapies for renal diseases, we encourage you to join our team. Based in the state-of-the-art Bakar Labs in Berkeley, CA, we are focused on pioneering medicines that make a meaningful impact.\n\nThe Role\n\nWe are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting in vivo research efforts, with a focus on rodent studies, animal colony management, and lab operation support. This is a projected year long contract.\n","description":"Company Overview
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\nAt Renasant Bio, we are driven by a singular goal: to change what’s possible for patients with kidney disease. ADPKD remains one of the most challenging areas in medicine, and we believe it requires bold thinking, rigorous science, and a team committed to doing things differently.
\nWe’re looking for individuals who bring both scientific rigor and creativity to hard problems, and who believe great work is built through respectful, direct collaboration. You communicate with honesty and transparency, adapt quickly as priorities evolve, and hold yourself—and others—to a high standard. Above all, you operate with urgency and purpose, grounded in the knowledge that patients are waiting.
\nBased at Bakar Labs in Berkeley, CA with additional support in Cambridge, MA, we are advancing new therapies designed to make a meaningful difference for patients.
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\nThe Role
\nWe are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting in vivo research efforts, with a focus on rodent studies, animal colony management, and lab operation support. This is a projected year long contract.
","id":"babe48b6-c128-48ae-a928-4d09257bb573","lists":[{"text":"Responsibilities","content":"\nCollaborate with scientists to evaluate novel therapeutic candidates using transgenic mouse models, including target validation and mechanism of action studies.\nOversee and maintain mouse colonies, including breeding, genotyping, colony expansion, and accurate inventory tracking of vivarium supplies.\nPerform routine in vivo tasks, including animal handling, dosing (PO, IV, IP, SC), blood and tissue collection, sample processing, anesthesia administration, and euthanasia as needed.\nMonitor animal health, maintain compliance with IACUC protocols, and ensure ethical standards in animal care.\nProvide detailed documentation of experimental protocols, observations, and results.\nCollaborate with multidisciplinary teams, contributing to discussions on in vivo models and study outcomes.\nAdapt to the evolving needs of the team and contribute to maintaining aggressive project timelines.\n"},{"text":"Requirements","content":"\nEducation: B.Sc degree in a relevant scientific field with 1-2 years of hands-on experience in preclinical research or a bachelor’s degree with equivalent relevant experience. Industry experience is advantageous but not required.\nIn Vivo Expertise: Proficiency in rodent handling required; experience with dosing techniques (e.g., IV, IP, SC), blood/tissue collection, and surgical techniques a plus.\nMouse Colony Management: Demonstrated experience in managing transgenic mouse colonies, including breeding, genotyping, and maintenance.\nLaboratory Skills: Experience with in vivo sample processing and preparation for downstream assays such as histology or molecular analyses.\nTeam Collaboration: Strong interpersonal skills with the ability to work collaboratively in a multidisciplinary environment.\nOrganization: Exceptional attention to detail, organizational skills, and the ability to manage multiple tasks efficiently.\nCommitment to Safety: Adherence to laboratory safety and ethical standards in animal research.\nFlexibility: Willingness to adapt to team priorities and timelines in a fast-paced environment.\n"}],"salaryRange":{"min":38.46,"currency":"USD","interval":"per-hour-wage","max":43.25},"salaryDescription":"Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Contractors will be eligible for health benefits and be paid via third party.
","salaryDescriptionPlain":"Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Contractors will be eligible for health benefits and be paid via third party.\n","text":"Contract Research Associate (In Vivo)","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"Company Overview
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\nAt Renasant Bio, we are driven by a singular goal: to change what’s possible for patients with kidney disease. ADPKD remains one of the most challenging areas in medicine, and we believe it requires bold thinking, rigorous science, and a team committed to doing things differently.
\nWe’re looking for individuals who bring both scientific rigor and creativity to hard problems, and who believe great work is built through respectful, direct collaboration. You communicate with honesty and transparency, adapt quickly as priorities evolve, and hold yourself—and others—to a high standard. Above all, you operate with urgency and purpose, grounded in the knowledge that patients are waiting.
\nBased at Bakar Labs in Berkeley, CA with additional support in Cambridge, MA, we are advancing new therapies designed to make a meaningful difference for patients.
\n
\nThe Role
\nWe are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting in vivo research efforts, with a focus on rodent studies, animal colony management, and lab operation support. This is a projected year long contract.
","descriptionBodyPlain":"Company Overview\n\nWe are looking for dedicated professionals who thrive on tackling complex challenges and are committed to improving the lives of patients. If you value innovation, collaboration, and integrity, and are eager to contribute to advancing therapies for renal diseases, we encourage you to join our team. Based in the state-of-the-art Bakar Labs in Berkeley, CA, we are focused on pioneering medicines that make a meaningful impact.\n\nThe Role\n\nWe are seeking a highly motivated Research Associate with a strong background in preclinical drug discovery and in vivo research. This individual will join our dynamic team and contribute to advancing our pipeline for kidney diseases. The ideal candidate will play a key role in supporting in vivo research efforts, with a focus on rodent studies, animal colony management, and lab operation support. This is a projected year long contract.\n","hostedUrl":"https://jobs.lever.co/5amventures/babe48b6-c128-48ae-a928-4d09257bb573","applyUrl":"https://jobs.lever.co/5amventures/babe48b6-c128-48ae-a928-4d09257bb573/apply"},{"additionalPlain":"","additional":"We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
","categories":{"commitment":"Full-time","department":"4:59 Initiative","location":"Emeryville, CA","team":"4:59 - Prolynx","allLocations":["Emeryville, CA"]},"createdAt":1777044673409,"descriptionPlain":"","description":"We are seeking a highly motivated, hands-on Director of Translational Pharmacology to lead and drive preclinical pharmacology efforts across our pipeline. This individual will play a central, decision-making role in translating innovative science into rigorous, in vivo proof-of-concept and clinically actionable pharmacology strategies.
","id":"76c67c55-5800-4e79-bbdb-ab3c293713e3","lists":[{"text":"","content":"\n
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Lead the design, execution, and interpretation of preclinical pharmacology studies supporting drug discovery and development programs \nDevelop and apply quantitative PK/PD models, integrating pharmacokinetics, pharmacodynamics, and chemical kinetics to guide compound optimization and dosing strategies \nDesign and oversee in vivo studies, including selection and development of appropriate animal models \nDrive rigorous data analysis, including statistical evaluation and modeling to inform decision-making\nTranslate preclinical findings into clinically relevant hypotheses and development strategies \nCollaborate closely with teams to optimize drug candidates and delivery systems \nContribute to regulatory documentation and strategy (IND-enabling studies, study reports, etc.) \nBuild and manage relationships with CROs and external collaborators \n\n\n
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PhD, MD, or equivalent in pharmacology, biomedical sciences, or related field \nSignificant experience in preclinical pharmacology within biotech or pharmaceutical settings \nExperience in choosing appropriate animal models \nDeep expertise in PK/PD modeling, with strong grounding in chemical kinetics and quantitative biology \nProven experience designing studies to evaluate drug combinations and synergy, including application of factorial experimental design Demonstrated experience designing and interpreting in vivo pharmacology studies \nExperience in advancing preclinical candidates through IND-enabling studies and contributing meaningfully to IND submissions \nStrong statistical and data analysis skills \nExperience in metabolic diseases, particularly obesity and/or diabetes, strongly preferred \n\n\n
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We are seeking a highly motivated, hands-on Director of Translational Pharmacology to lead and drive preclinical pharmacology efforts across our pipeline. This individual will play a central, decision-making role in translating innovative science into rigorous, in vivo proof-of-concept and clinically actionable pharmacology strategies.
","descriptionBodyPlain":"","hostedUrl":"https://jobs.lever.co/5amventures/76c67c55-5800-4e79-bbdb-ab3c293713e3","applyUrl":"https://jobs.lever.co/5amventures/76c67c55-5800-4e79-bbdb-ab3c293713e3/apply"},{"additionalPlain":"We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.\n","additional":"\n
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We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
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In this newly created role, as a Process Development Engineer I, you will work in close collaboration with our Process Development team, and our Senior Process Engineer in particular, to advance our manufacturing process technology for drug-releasing microspheres, as we begin scale-up to enable later phase GMP production. Key aspects of your role include oversight and hands-on validation of our process that employs custom equipment, identifying process improvements, troubleshooting complex issues, generating manufacturing method SOPs, and maintaining a controlled inventory of equipment parts and records within our GMP-like Quality Management System (QMS).
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This role involves hands-on process development in our lab, process technology research, and reporting and record keeping. We’re looking for an extremely organized, critical problem solver who brings experience that may include process chemistry, mechanical engineering, GMP manufacturing, process equipment maintenance, process automation, and knowledge of record keeping within a QMS.
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Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Employees are also eligible for performance bonuses, equity participation and comprehensive health benefits.
","salaryDescriptionPlain":"Final compensation will be based on a candidate’s qualifications, experience, and geographic location. Employees are also eligible for performance bonuses, equity participation and comprehensive health benefits.\n","text":"Process Development Engineer","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"\n
In this newly created role, as a Process Development Engineer I, you will work in close collaboration with our Process Development team, and our Senior Process Engineer in particular, to advance our manufacturing process technology for drug-releasing microspheres, as we begin scale-up to enable later phase GMP production. Key aspects of your role include oversight and hands-on validation of our process that employs custom equipment, identifying process improvements, troubleshooting complex issues, generating manufacturing method SOPs, and maintaining a controlled inventory of equipment parts and records within our GMP-like Quality Management System (QMS).
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This role involves hands-on process development in our lab, process technology research, and reporting and record keeping. We’re looking for an extremely organized, critical problem solver who brings experience that may include process chemistry, mechanical engineering, GMP manufacturing, process equipment maintenance, process automation, and knowledge of record keeping within a QMS.
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We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
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We are seeking an experienced, highly quantitative scientist to lead bioanalytical strategy and quality control across a diverse portfolio of peptide, protein, and small molecule therapeutics. This individual will define analytical approaches, oversee external CROs, and ensure that all data generated are accurate, reproducible, and decision-grade.
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This role is ideal for someone who combines deep knowledge of bioanalytical methods with a strong QC mindset and the ability to diagnose and resolve complex analytical challenges across multiple assay platforms.
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Preferred Qualifications
\n\nExperience across multiple molecular modalities (peptides, monoclonal antibodies, small molecules)\nBackground in analytical development or QC for regulated products\nExperience supporting IND-enabling studies or clinical programs\nFamiliarity with complex or long-acting drug delivery systems\n"},{"text":"","content":"\nOwn bioanalytical strategy\n\nDefine fit-for-purpose analytical approaches for PK, PD, and mechanistic studies\nSelect appropriate assay platforms (ligand-binding, LC-MS-based, hybrid methods)\n\n\nLead CRO oversight\n\nDesign and manage outsourced bioanalytical studies\nCritically review assay development, validation, and sample analysis\nIdentify deficiencies in methods, data quality, or interpretation and drive resolution\n\n\nEnsure quantitative rigor and data integrity\n\nEvaluate calibration models, LLOQ, accuracy/precision, and assay robustness\nDetect and troubleshoot issues such as matrix effects, instability, adsorption, and assay interference\nEstablish internal standards for data quality across programs\n\n\nApply QC and regulatory principles\n\nEnsure methods and datasets meet GLP and regulatory expectations (e.g., ICH M10)\nContribute to analytical sections of IND-enabling packages and regulatory filings\nImplement quality systems and documentation standards where needed\n\n\nSupport cross-functional decision making\n\nWork closely with PK/PD, biology, and clinical teams to interpret data correctly\nDistinguish analytical artifacts from true biological signals\nProvide clear recommendations based on quantitative evidence\n\n\nOperate across modalities\n\nApply consistent analytical thinking across peptides, biologics, and small molecules\nEnsure comparability and continuity of data across platforms and studies\n\n\n"}],"salaryRange":{"min":140000,"max":170000,"currency":"USD","interval":"per-year-salary"},"text":"QC Analytical Scientist","country":"US","workplaceType":"onsite","opening":"","openingPlain":"","descriptionBody":"\n
We are seeking an experienced, highly quantitative scientist to lead bioanalytical strategy and quality control across a diverse portfolio of peptide, protein, and small molecule therapeutics. This individual will define analytical approaches, oversee external CROs, and ensure that all data generated are accurate, reproducible, and decision-grade.
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This role is ideal for someone who combines deep knowledge of bioanalytical methods with a strong QC mindset and the ability to diagnose and resolve complex analytical challenges across multiple assay platforms.
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